概述

  • 产品名称Anti-ARHGAP21抗体
  • 描述
    兔多克隆抗体to ARHGAP21
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: VPPCLTTSAP LIRRQLSHDH ESVGPPSLDA QPNSKTERSK SYDEGLDDYR EDAKLSFKHV SSLKGIKIAD SQKSSEDSGS RKDSSSEVFS DAAKEG, corresponding to amino acids 840-935 of Human ARHGAP21.

  • 阳性对照
    • Human gall bladder tissue.

性能

应用

Our Abpromise guarantee covers the use of ab122350 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions.
  • 组织特异性Widely expressed with higher expression in brain, heart, skeletal muscle and placenta.
  • 序列相似性Contains 1 PDZ (DHR) domain.
    Contains 1 PH domain.
    Contains 1 Rho-GAP domain.
  • 细胞定位Golgi apparatus membrane. Cell junction. Cytoplasmic vesicle membrane. Cytoplasm > cytoskeleton. Localization to the Golgi is dependent on interaction with GTP-bound ARF1.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Arhgap21 antibody
    • KIAA1424 antibody
    • RHG21_HUMAN antibody
    • Rho GTPase-activating protein 10 antibody
    • Rho GTPase-activating protein 21 antibody
    • Rho-type GTPase-activating protein 21 antibody
    see all

Anti-ARHGAP21 antibody 图像

  • ab122350, at 1/200 dilution, staining ARHGAP21 in paraffin-embedded Human gall bladder tissue by Immunohistochemistry.

Anti-ARHGAP21 antibody (ab122350)参考文献

ab122350 has not yet been referenced specifically in any publications.

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