概述

  • 产品名称Anti-ARHGAP20抗体
    参阅全部 ARHGAP20 一抗
  • 描述
    小鼠多克隆抗体to ARHGAP20
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    ARHGAP20 (NP_065860, 1 a.a. ~ 1191 a.a) human protein.

  • 阳性对照
    • Rat brain tissue lysate, ARHGAP20 transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab68918 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 150 kDa (predicted molecular weight: 132 kDa).

靶标

  • 功能GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
  • 组织特异性Expressed predominantly in the brain. Lower expression is found in lymph nodes.
  • 疾病相关Note=A chromosomal aberration involving ARHGAP20 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL). Translocation t(X;11)(q21;q23) with BRWD3 does not result in fusion transcripts but disrupts both genes.
  • 序列相似性Contains 1 PH domain.
    Contains 1 Ras-associating domain.
    Contains 1 Rho-GAP domain.
  • 发展阶段Low expression is found in fetal liver.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Arhgap20 antibody
    • KIAA1391 antibody
    • RARHOGAP antibody
    • RHG20_HUMAN antibody
    • Rho GTPase activating protein 20 antibody
    • Rho GTPase-activating protein 20 antibody
    • Rho type GTPase activating protein 20 antibody
    • Rho-type GTPase-activating protein 20 antibody
    see all

Anti-ARHGAP20 antibody 图像

  • Anti-ARHGAP20 antibody (ab68918) at 1/500 dilution + rat brain lysate at 25 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 132 kDa
    Observed band size : 132 kDa
    Additional bands at : 55 kDa. We are unsure as to the identity of these extra bands.
  • All lanes : Anti-ARHGAP20 antibody (ab68918) at 1/500 dilution

    Lane 1 : transfected 293T cell lysate
    Lane 2 : non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 132 kDa
    Observed band size : 150 kDa (why is the actual band size different from the predicted?)

Anti-ARHGAP20 antibody (ab68918)参考文献

ab68918 has not yet been referenced specifically in any publications.

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