概述

  • 产品名称Anti-Arg2抗体
    参阅全部 Arg2 一抗
  • 描述
    兔多克隆抗体to Arg2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide from within the C termina amino acids 289-338 (SALDLVEVNP QLATSEEEAK TTANLAVDVI ASSFGQTREG GHIVYDQLPT) of Human Arg2 (NP_001163)

  • 阳性对照
    • Jurkat cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab81505 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 36 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.
  • 组织特异性Expressed most strongly in kidney and prostate, much less strongly in the brain, skeletal muscle, placenta, lung, mammary gland, macrophage, uterus, testis and gut, but apparently not in the liver, heart and pancreas.
  • 通路Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.
  • 序列相似性Belongs to the arginase family.
  • 细胞定位Mitochondrion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ARG2 antibody
    • ARGI2_HUMAN antibody
    • Arginase II mitochondrial antibody
    • Arginase type II antibody
    • Arginase-2 antibody
    • arginase-2, mitochondrial antibody
    • Kidney arginase antibody
    • Kidney type arginase antibody
    • Kidney-type arginase antibody
    • L arginine amidinohydrolase antibody
    • L arginine ureahydrolase antibody
    • mitochondrial antibody
    • Non hepatic arginase antibody
    • Non-hepatic arginase antibody
    • Nonhepatic arginase antibody
    • Type II arginase antibody
    see all

Anti-Arg2 antibody 图像

  • Anti-Arg2 antibody (ab81505) at 1 µg/ml + Jurkat cell lysate at 10 µg with skim milk/ PBS buffer at 5 %

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 36 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)

Anti-Arg2 antibody (ab81505)参考文献

This product has been referenced in:
  • Lukasova M  et al. Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells. J Clin Invest 121:1163-73 (2011). IHC-Fr ; Mouse . Read more (PubMed: 21317532) »

See 1 Publication for this product

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