概述

  • 产品名称Anti-ARA9抗体
    参阅全部 ARA9 一抗
  • 描述
    兔多克隆抗体to ARA9
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, African Green Monkey, Chinese Hamster, Orangutan, Elephant
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 280-330 of Human ARA9 (NP_003968.2).

  • 阳性对照
    • HeLa, Jurkat and 293T whole cell lysates.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% Tris citrate/phosphate
    Note: pH 7 to 8
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab125163 was affinity purified using an epitope specific to AIP immobilized on solid support .
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab125163 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/5000. Predicted molecular weight: 37 kDa.
IP Use at 2-10 µg/mg of lysate.

靶标

  • 功能May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.
    Cellular negative regulator of the hepatitis B virus (HBV) X protein.
  • 组织特异性Widely expressed. Higher levels seen in the heart, placenta and skeletal muscle. Not expressed in the liver.
  • 疾病相关Defects in AIP are a cause of familial isolated pituitary adenoma (FIPA) [MIM:102200].
    Defects in AIP are a cause of growth hormone-secreting pituitary adenoma (GHSPA) [MIM:102200]; also known as familial isolated somatotropinomas (FIS) or isolated familial somatotropinoma (IFS) or familial somatotrophinoma or acromegaly due to pituitary adenoma.
    Defects in AIP are a cause of ACTH-secreting pituitary adenoma (ASPA) [MIM:219090]; also known as pituitary Cushing disease. A pituary adenoma resulting in excessive production of adrenocorticotropic hormone. This leads to hypersecretion of cortisol by the adrenal glands and ACTH-dependent Cushing syndrome. Clinical manifestations of Cushing syndrome include facial and trunkal obesity, abdominal striae, muscular weakness, osteoporosis, arterial hypertension, diabetes.
    Defects in AIP are a cause of prolactin-secreting pituitary adenoma (PSPA) [MIM:600634]; also known as prolactinoma. Prolactin-secreting pituitary adenoma is the most common type of hormonally active pituitary adenoma.
  • 序列相似性Contains 1 PPIase FKBP-type domain.
    Contains 2 TPR repeats.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AH receptor interacting protein antibody
    • AH receptor-interacting protein antibody
    • AIP antibody
    • AIP_HUMAN antibody
    • ARA 9 antibody
    • ARA9 antibody
    • Aryl hydrocarbon receptor interacting protein antibody
    • Aryl-hydrocarbon receptor-interacting protein antibody
    • fa03h10 antibody
    • FKBP 16 antibody
    • FKBP 37 antibody
    • FKBP16 antibody
    • FKBP37 antibody
    • HBV X associated protein 2 antibody
    • HBV X associated protein antibody
    • HBV X-associated protein 2 antibody
    • HBVX associated protein antibody
    • Immunophilin homolog ARA 9 antibody
    • Immunophilin homolog ARA9 antibody
    • SMTPHN antibody
    • XAP 2 antibody
    • XAP-2 antibody
    • XAP2 antibody
    see all

Anti-ARA9 antibody 图像

  • All lanes : Anti-ARA9 antibody (ab125163) at 0.4 µg/ml

    Lane 1 : 293T whole cell lysate at 50 µg
    Lane 2 : 293T whole cell lysate at 15 µg
    Lane 3 : Jurkat whole cell lysate at 50 µg
    Lane 4 : HeLa whole cell lysate at 50 µg

    Developed using the ECL technique

    Predicted band size : 37 kDa


    Exposure time : 30 seconds
  • Detection of ARA9 by Western Blot of Immunprecipitate.
    ab125163 at 1µg/ml staining ARA9 in 293T whole cell lysate immunoprecipitated using ab125163 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
    Detection: Chemiluminescence with exposure time of 10 seconds.

Anti-ARA9 antibody (ab125163)参考文献

ab125163 has not yet been referenced specifically in any publications.

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