概述

  • 产品名称Anti-Aquaporin 9抗体
    参阅全部 Aquaporin 9 一抗
  • 描述
    鸡多克隆抗体to Aquaporin 9
  • 特异性The 18 AA peptide was found to be unique to Aquaporin 9 without significant homology to any other Aquaporins. It has 72% homology with human Aquaporin 9. Aquaporin 9 from other species are yet to be cloned.
  • 经测试应用适用于: WB, ELISA, IHC-Fr, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse, Human
  • 免疫原

    An 18 AA synthetic peptide within the C-terminal domain of rat Aquaporin 9. This domain is predicted to be cytoplasmic. The immunising peptide is unique to Aquaporin 9 without significant homology to any other Aquaporins.

  • 常规说明The control peptide, because of its low MW (<3kD), is not suitable for Western blotting. It should be used for ELISA or antibody blocking to confirm antibody specificity. We recommend the use of 0.5-1% milk in all primary/secondary antibody-enzyme conjugate incubations in order to suppress non-specific bands.

性能

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应用

Our Abpromise guarantee covers the use of ab15129 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
IHC-Fr
IHC-P
ICC/IF
  • 应用说明ELISA: 1/10000 - 1/50000.
    IF: 1/500.
    IHC-P: 1/500.
    IHC-Fr: 1/75.
    WB: 1/1000 - 1/5000. Predicted molecular weight: 35.4 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol.
    • 组织特异性Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen.
    • 序列相似性Belongs to the MIP/aquaporin (TC 1.A.8) family.
    • 结构域Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AQP 9 antibody
      • AQP-9 antibody
      • Aqp9 antibody
      • AQP9_HUMAN antibody
      • Aquaglyceroporin-9 antibody
      • Aquaporin-9 antibody
      • Aquaporin9 antibody
      • HsT 17287 antibody
      • HsT17287 antibody
      • Small solute channel 1 antibody
      • SSC 1 antibody
      • SSC1 antibody
      see all

    Anti-Aquaporin 9 antibody (ab15129)参考文献

    This product has been referenced in:
    • Blomqvist SR  et al. Epididymal expression of the forkhead transcription factor Foxi1 is required for male fertility. EMBO J 25:4131-41 (2006). Read more (PubMed: 16932748) »

    See 1 Publication for this product

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