Anti-Aquaporin 9/AQP-9抗体(ab15129)
Key features and details
- Chicken polyclonal to Aquaporin 9/AQP-9
- Suitable for: ELISA
- Reacts with: Rat
- Isotype: IgY
概述
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产品名称
Anti-Aquaporin 9/AQP-9抗体
参阅全部 Aquaporin 9/AQP-9 一抗 -
描述
鸡多克隆抗体to Aquaporin 9/AQP-9 -
宿主
Chicken -
经测试应用
适用于: ELISAmore details -
种属反应性
与反应: Rat
预测可用于: Mouse, Human -
免疫原
Synthetic peptide corresponding to Rat Aquaporin 9/AQP-9 (C terminal).
Database link: P56627 -
常规说明
The control peptide, because of its low MW (<3kD), is not suitable for Western blotting. It should be used for ELISA or antibody blocking to confirm antibody specificity. We recommend the use of 0.5-1% milk in all primary/secondary antibody-enzyme conjugate incubations in order to suppress non-specific bands.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Constituents: Whole serum, 40% Glycerol -
Concentration information loading...
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纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgY -
研究领域
相关产品
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab15129于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ELISA |
1/100000.
|
说明 |
---|
ELISA
1/100000. |
靶标
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功能
Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol. -
组织特异性
Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen. -
序列相似性
Belongs to the MIP/aquaporin (TC 1.A.8) family. -
结构域
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA). -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 366 Human
- Entrez Gene: 64008 Mouse
- Entrez Gene: 65054 Rat
- Omim: 602914 Human
- SwissProt: O43315 Human
- SwissProt: Q9JJJ3 Mouse
- SwissProt: P56627 Rat
- Unigene: 104624 Human
see all -
别名
- AQP 9 antibody
- AQP-9 antibody
- Aqp9 antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (7)
ab15129 被引用在 7 文献中.
- Wu J et al. LncRNA MALAT1 promotes neuropathic pain progression through the miR-154-5p/AQP9 axis in CCI rat models. Mol Med Rep 21:291-303 (2020). PubMed: 31746418
- Liao S et al. Aquaporin 9 inhibits growth and metastasis of hepatocellular carcinoma cells via Wnt/ß-catenin pathway. Aging (Albany NY) 12:1527-1544 (2020). PubMed: 31969493
- Mori S et al. Aqp9 Gene Deletion Enhances Retinal Ganglion Cell (RGC) Death and Dysfunction Induced by Optic Nerve Crush: Evidence that Aquaporin 9 Acts as an Astrocyte-to-Neuron Lactate Shuttle in Concert with Monocarboxylate Transporters To Support RGC Function and Survival. Mol Neurobiol 57:4530-4548 (2020). PubMed: 32748371
- Huang X et al. Regulation mechanism of aquaporin 9 gene on inflammatory response and cardiac function in rats with myocardial infarction through extracellular signal-regulated kinase1/2 pathway. Heart Vessels 34:2041-2051 (2019). PubMed: 31218464
- Xiang T et al. The possible association between AQP9 in the intestinal epithelium and acute liver injury-induced intestinal epithelium damage. Mol Med Rep 18:4987-4993 (2018). PubMed: 30320400
- Ma W et al. Zika Virus Causes Testis Damage and Leads to Male Infertility in Mice. Cell 167:1511-1524.e10 (2016). PubMed: 27884405
- Blomqvist SR et al. Epididymal expression of the forkhead transcription factor Foxi1 is required for male fertility. EMBO J 25:4131-41 (2006). PubMed: 16932748