概述

  • 产品名称Anti-Aquaporin 9抗体
    参阅全部 Aquaporin 9 一抗
  • 描述
    兔多克隆抗体to Aquaporin 9
  • 特异性The 18 AA peptide was found to be unique to Aquaporin 9 without significant homology to any other aquaporins. It has 72% homology with human Aquaporin 9. Aquaporin 9 from other species are yet to be cloned.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    An 18 AA synthetic peptide within the C-terminal domain of rat Aquaporin 9. This domain is predicted to be cytoplasmic (unfortunately, the amino acid sequence is considered to be commercially sensitive).

性能

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应用

Our Abpromise guarantee covers the use of ab15127 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: 1/10,000 - 1/50,000, or 0.5-1 ug/ml for affinity purified antibody. Control peptide can be used to coat ELISA plates at 1 ug/ml.
    WB: 1/1000 - 1/5000, or 1-10 ug/ml for affinity purified antibody using ECL. Predicted molecular weight: 35.4 kDa.
    Immunohistochemistry & Immunofluorescence: Neat serum can be used at 1:500 or more.

    Control peptides, because of their low MW (<3kD), are not suitable for Western. It should be used for ELISA or antibody blocking to confirm antibody specificity

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol.
    • 组织特异性Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen.
    • 序列相似性Belongs to the MIP/aquaporin (TC 1.A.8) family.
    • 结构域Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AQP 9 antibody
      • AQP-9 antibody
      • Aqp9 antibody
      • AQP9_HUMAN antibody
      • Aquaglyceroporin-9 antibody
      • Aquaporin-9 antibody
      • Aquaporin9 antibody
      • HsT 17287 antibody
      • HsT17287 antibody
      • Small solute channel 1 antibody
      • SSC 1 antibody
      • SSC1 antibody
      see all

    Anti-Aquaporin 9 antibody (ab15127)参考文献

    This product has been referenced in:
    • Sun Z  et al. Recombinant hirudin treatment modulates aquaporin-4 and aquaporin-9 expression after intracerebral hemorrhage in vivo. Mol Biol Rep 36:1119-27 (2009). WB, IF, IHC ; Rat . Read more (PubMed: 18574711) »

    See 1 Publication for this product

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    We currently have no matching products to the rat extracelluar dom...

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    This antibody recognizes Aquaporin 9. There is no significant sequence homology to any other AQPs. Species Crossreactivity: Human, mouse and rat. Species Sequence Homology: Mouse: 94%; human: 72%. For a polyclonal =70% is usually good enough to ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"