Anti-Aquaporin 5抗体(ab15119)

概述

  • 产品名称Anti-Aquaporin 5抗体
    参阅全部 Aquaporin 5 一抗
  • 描述
    兔多克隆抗体to Aquaporin 5
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide with N terminally added cysteine (Rat) conjugated to KLH (C terminal).

性能

应用

Our Abpromise guarantee covers the use of ab15119 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/5000. Predicted molecular weight: 29 kDa.
ELISA 1/10000 - 1/50000.

靶标

  • 功能Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions. Required for TRPV4 activation by hypotonicity (PubMed:16571723). Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells (PubMed:16571723).
  • 疾病相关Keratoderma, palmoplantar, Bothnian type
  • 序列相似性Belongs to the MIP/aquaporin (TC 1.A.8) family.
  • 结构域Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
  • 细胞定位Apical cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AQP 5 antibody
    • AQP-5 antibody
    • AQP5 antibody
    • AQP5_HUMAN antibody
    • Aquaporin 5 antibody
    • Aquaporin-5 antibody
    see all

Anti-Aquaporin 5 antibody (ab15119)参考文献

ab15119 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Mouse Tissue sections (epididymis)
Specification epididymis
Fixative Buin's solution
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: citrate buffer
Permeabilization No
Blocking step Serum as blocking agent for 30 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Username

Abcam user community

Verified customer

提交于 Apr 30 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"