Anti-Aquaporin 4抗体(ab125049)

概述

  • 产品名称Anti-Aquaporin 4抗体
    参阅全部 Aquaporin 4 一抗
  • 描述
    兔多克隆抗体to Aquaporin 4
  • 经测试应用适用于: ICC/IF, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide:

    N-CTKGSYMEVEDNRSQVETED

    , corresponding to C terminal amino acids 273-291 of Rat Aquaporin 4 (NP_036957.1).

  • 阳性对照
    • Rat kidney lysate; Rat kidney tissue

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab125049 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF 1/200 - 1/400.
WB 1/1000 - 1/4000. Predicted molecular weight: 35 kDa.

靶标

  • 功能Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
  • 组织特异性Brain - muscle >> heart, kidney, lung, and trachea.
  • 序列相似性Belongs to the MIP/aquaporin (TC 1.A.8) family.
  • 结构域Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
  • 翻译后修饰Phosphorylation by PKC at Ser-180 reduces conductance by 50%. Phosphorylation by PKG at Ser-111 in response to glutamats increases conductance by 40%.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AQP 4 antibody
    • AQP-4 antibody
    • AQP4 antibody
    • AQP4_HUMAN antibody
    • Aquaporin type 4 antibody
    • Aquaporin-4 antibody
    • Aquaporin4 antibody
    • HMIWC 2 antibody
    • HMIWC2 antibody
    • Mercurial insensitive water channel antibody
    • Mercurial-insensitive water channel antibody
    • MGC22454 antibody
    • MIWC antibody
    • WCH 4 antibody
    • WCH4 antibody
    see all

Anti-Aquaporin 4 antibody 图像

  • All lanes : Anti-Aquaporin 4 antibody (ab125049) at 1/2000 dilution

    Lane 1 : Rat kidney lysate
    Lane 2 : Rat kidney lysate


    Predicted band size : 35 kDa
  • ab125049, at 1/200 dilution, staining Aquaporin 4 in Rat kidney tissue by Immunofluorescence.

Anti-Aquaporin 4 antibody (ab125049)参考文献

ab125049 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab125049.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"