Anti-Aquaporin 1抗体[10C11] (ab117970)

概述

  • 产品名称Anti-Aquaporin 1抗体[10C11]
    参阅全部 Aquaporin 1 一抗
  • 描述
    小鼠单克隆抗体[10C11] to Aquaporin 1
  • 经测试应用适用于: WB, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length recombinant Human Aquaporin 1 produced in HEK293T cells (NP_932766).

  • 阳性对照
    • HEK293T cells transfected with pCMV6-ENTRY Aquaporin 1; HEK293T cells transfected with RC205304 overexpressing plasmid.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 48% PBS, 1% BSA, 50% Glycerol
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明ab117970 is purified from Mouse ascites fluids by affinity chromatography.
  • 克隆单克隆
  • 克隆编号10C11
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab117970 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000. Predicted molecular weight: 29 kDa.
Flow Cyt 1/100. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
  • 组织特异性Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver.
  • 序列相似性Belongs to the MIP/aquaporin (TC 1.A.8) family.
  • 结构域Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AQP 1 antibody
    • AQP CHIP antibody
    • AQP-1 antibody
    • AQP1 antibody
    • AQP1_HUMAN antibody
    • aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group) antibody
    • aquaporin 1 (Colton blood group) antibody
    • Aquaporin CHIP antibody
    • Aquaporin-1 antibody
    • Aquaporin-CHIP antibody
    • Aquaporin1 antibody
    • Channel forming integral protein 28kDa antibody
    • Channel like integral membrane protein 28 kDa antibody
    • CHIP 28 antibody
    • CHIP28 antibody
    • CO antibody
    • Colton blood group antibody
    • Growth factor induced delayed early response protein antibody
    • MGC26324 antibody
    • Urine water channel antibody
    • Water channel protein CHIP 29 antibody
    • Water channel protein CHIP29 antibody
    • Water channel protein for red blood cells and kidney proximal tubule antibody
    see all

Anti-Aquaporin 1 antibody [10C11] 图像

  • All lanes : Anti-Aquaporin 1 antibody [10C11] (ab117970) at 1/2000 dilution

    Lane 1 : HEK293T cell lysate, transfected with pCMV6-ENTRY control
    Lane 2 : HEK293T cell lysate, transfected with pCMV6-ENTRY Aquaporin 1

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 29 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC205304)
  • HEK293T cells transfected with either RC205304 overexpressing plasmid (Red) or empty vector control plasmid (Blue) were immunostained by ab117970 at a dilution of 1/100, and then analyzed by flow cytometry.

Anti-Aquaporin 1 antibody [10C11] (ab117970)参考文献

ab117970 has not yet been referenced specifically in any publications.

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