概述

  • 产品名称Anti-APXL抗体
    参阅全部 APXL 一抗
  • 描述
    兔多克隆抗体to APXL
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within the internal sequence amino acids 1296-1345 of Human APXL (

    TSPPGLSYMKAKEKTVEDLKSEELAREIVGKDKSLADILDPSVKIKTTMD

    ); NP_001640

  • 阳性对照
    • Fetal lung lysate (Human)

性能

应用

Our Abpromise guarantee covers the use of ab86265 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 176 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution.
  • 组织特异性Abundant in retina and melanoma; also in brain, placenta, lung, kidney and pancreas.
  • 序列相似性Belongs to the shroom family.
    Contains 1 ASD1 domain.
    Contains 1 ASD2 domain.
    Contains 1 PDZ (DHR) domain.
  • 结构域The ASD1 domain mediates F-actin binding.
  • 细胞定位Apical cell membrane. Cell junction > tight junction. Cytoplasm > cytoskeleton. Associates with cortical F-actin.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 4832440C16 antibody
    • Ab2-404 antibody
    • Apical like protein antibody
    • Apical like protein APXL protein antibody
    • apical protein of Xenopus-like antibody
    • Apical protein Xenopus laevis like antibody
    • apical protein, Xenopus laevis-like antibody
    • apical protein-like antibody
    • apical protein-like (Xenopus laevis) antibody
    • Apical-like protein antibody
    • APX homolog of Xenopus antibody
    • C630003H05Rik antibody
    • DKFZp781J074 antibody
    • FLJ39277 antibody
    • HSAPXL antibody
    • Liver regeneration-related protein LRRG167 antibody
    • OTTHUMP00000022887 antibody
    • Protein Apxl antibody
    • Protein Shroom2 antibody
    • Shrm2 antibody
    • SHRM2_HUMAN antibody
    • SHROOM 2 antibody
    • Shroom family member 2 antibody
    • shroom2 antibody
    see all

Anti-APXL antibody 图像

  • Anti-APXL antibody (ab86265) at 1 µg/ml (in 5% skim milk / PBS buffer) + Fetal lung lysate (Human) at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 176 kDa
    Observed band size : 176 kDa
    Additional bands at : 90 kDa. We are unsure as to the identity of these extra bands.

Anti-APXL antibody (ab86265)参考文献

ab86265 has not yet been referenced specifically in any publications.

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