The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 176 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
功能May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution.
组织特异性Abundant in retina and melanoma; also in brain, placenta, lung, kidney and pancreas.
序列相似性Belongs to the shroom family. Contains 1 ASD1 domain. Contains 1 ASD2 domain. Contains 1 PDZ (DHR) domain.