概述

  • 产品名称Anti-Aprotinin抗体[35]
  • 描述
    小鼠单克隆抗体[35] to Aprotinin
  • 经测试应用适用于: WB, Indirect ELISAmore details
  • 种属反应性
    与反应: Cow
  • 免疫原

    Aprotinin from bovine lung adsorbed onto aluminum hydroxide gel

  • 阳性对照
    • Bovine lung

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 15mM Sodium Azide
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号35
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab82110 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 11 kDa.
Indirect ELISA 1/33000.

靶标

  • 相关性Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. It is present in blood and in most tissues, with a high concentration in lung, inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, Aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins. Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids arranged in a single polypeptide chain, cross-linked by three disulfide bridges.
  • 细胞定位Secreted
  • 数据库链接
  • 别名
    • Basic protease inhibitor antibody
    • BPI antibody
    • BPTI antibody
    • Pancreatic trypsin inhibitor antibody
    • PTI antibody
    see all

Anti-Aprotinin antibody [35] (ab82110)参考文献

This product has been referenced in:
  • Zlokovic BV  et al. Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer's amyloid ß-peptide elimination from the brain. J Neurochem 115:1077-89 (2010). WB, ELISA . Read more (PubMed: 20854368) »

See 1 Publication for this product

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Thank you for contacting us and your interest in our products.

The two anti-aprotinin antibodies we have in our catalogue (ab82110 and ab121046) have both been raised against full length aprotinin from cow (SwissProt reference http://www.unip...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"