Anti-Apoptosis inhibitor 5抗体(ab65068)


  • 产品名称Anti-Apoptosis inhibitor 5抗体
    参阅全部 Apoptosis inhibitor 5 一抗
  • 描述
    兔多克隆抗体to Apoptosis inhibitor 5
  • 经测试应用适用于: ELISA, IHC-P, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide derived from C-terminus of human Apoptosis inhibitor 5

  • 阳性对照
    • Human heart tissue, extracts from 293, Jurkat and HUVEC cells.



Our Abpromise guarantee covers the use of ab65068 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/20000.
IHC-P 1/50 - 1/100.
WB 1/500 - 1/1000. Detects a band of approximately 58 kDa (predicted molecular weight: 58 kDa).


  • 功能Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
  • 组织特异性Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in heart, pancreas and placenta. Highly expressed in several cancers. Preferentially expressed in squamous cell carcinoma versus adenocarcinoma in non-small cell lung cancer.
  • 序列相似性Belongs to the API5 family.
  • 结构域Two regions, an N-terminal (aa 96-107) and a C-terminal (aa 274-311) are required for binding FGF2.
  • 细胞定位Cytoplasm and Nucleus. Cytoplasm. Mainly nuclear. Can also be cytoplasmic.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AAC 11 antibody
    • AAC-11 antibody
    • AAC11 antibody
    • Antiapoptosis clone 11 protein antibody
    • API 5 antibody
    • API-5 antibody
    • api5 antibody
    • API5 like 1 antibody
    • API5_HUMAN antibody
    • API5L1 antibody
    • Apoptosis inhibitor 5 antibody
    • Cell migration inducing gene 8 protein antibody
    • Cell migration-inducing gene 8 protein antibody
    • Fibroblast growth factor 2 interacting factor 2 antibody
    • Fibroblast growth factor 2-interacting factor antibody
    • FIF antibody
    • MIG 8 antibody
    • MIG8 antibody
    • Migration inducing protein MIG8 antibody
    • Protein XAGL antibody
    see all

Anti-Apoptosis inhibitor 5 antibody 图像

  • All lanes : Anti-Apoptosis inhibitor 5 antibody (ab65068) at 1/500 dilution

    Lane 1 : extracts from 293 cells
    Lane 2 : extracts from Jurkat cells
    Lane 3 : extracts from HuvEc cells
    Lane 4 : extracts from HuvEc cells with immunizing peptide at 5 µg

    Lysates/proteins at 5 µg per lane.

    Predicted band size : 58 kDa
    Observed band size : 58 kDa
    Additional bands at : 26 kDa,65 kDa. We are unsure as to the identity of these extra bands.
  • ab65068 at 1/50 dilution staining human heart tissue without (left) and with (right) immunzing peptide; paraffin embedded.

Anti-Apoptosis inhibitor 5 antibody (ab65068)参考文献

ab65068 has not yet been referenced specifically in any publications.

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