功能Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL. May be involved in myocardium-protective mechanisms against lipid accumulation.
组织特异性Expressed in all tissues examined. Up-regulated in diabetic heart.
序列相似性Belongs to the apolipoprotein O family.
翻译后修饰O-glycosylation; glycosaminoglycan of chondroitin-sulfate type.