重组Anti-Apo-H抗体[EPR2898(2)] (ab108348)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR2898(2)] to Apo-H
- Suitable for: WB, ICC/IF
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-Apo-H抗体[EPR2898(2)]
参阅全部 Apo-H 一抗 -
描述
兔单克隆抗体[EPR2898(2)] to Apo-H -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details
不适用于: Flow Cyt or IHC-P -
种属反应性
与反应: Human
预测可用于: Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- Human fetal liver, Human plasma, human fetal kidney, and HDL lysates, HepG2 cells
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
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纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
EPR2898(2) -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab108348于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/10000 - 1/50000. Predicted molecular weight: 38 kDa.
|
|
ICC/IF |
1/100.
|
说明 |
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WB
1/10000 - 1/50000. Predicted molecular weight: 38 kDa. |
ICC/IF
1/100. |
靶标
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功能
Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. -
组织特异性
Expressed by the liver and secreted in plasma. -
序列相似性
Contains 4 Sushi (CCP/SCR) domains. -
翻译后修饰
N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 350 Human
- Entrez Gene: 287774 Rat
- Omim: 138700 Human
- SwissProt: P02749 Human
- SwissProt: P26644 Rat
- Unigene: 445358 Human
- Unigene: 1824 Rat
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别名
- Activated protein C binding protein antibody
- Activated protein C-binding protein antibody
- Anticardiolipin cofactor antibody
see all
图片
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Immunofluorescent staining of HepG2 cells using ab108348 at a dilution of 1/100.
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All lanes : Anti-Apo-H antibody [EPR2898(2)] (ab108348) at 1/10000 dilution
Lane 1 : Human fetal liver lysate
Lane 2 : Human plasma lysate
Lane 3 : Human fetal kidney lysate
Lane 4 : HDL lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 38 kDa
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab108348 被引用在 3 文献中.
- Ho YC et al. Further Investigations of the Effects of Anti-ß2GP1 Antibodies on Collagen-Induced Platelet Aggregation. Clin Appl Thromb Hemost 24:1128-1133 (2018). PubMed: 29121809
- Sá E Cunha C et al. Plasmodium berghei EXP-1 interacts with host Apolipoprotein H duringPlasmodiumliver-stage development. Proc Natl Acad Sci U S A 114:E1138-E1147 (2017). PubMed: 28137845
- Yao Y et al. Screening and identification of potential predictive biomarkers for Down's syndrome from second trimester maternal serum. Expert Rev Proteomics 12:97-107 (2015). WB ; Human . PubMed: 25434962