概述

  • 产品名称Anti-Apolipoprotein D抗体[8CD6]
    参阅全部 Apolipoprotein D 一抗
  • 描述
    小鼠单克隆抗体[8CD6] to Apolipoprotein D
  • 特异性APO-D is localized to steroid-responsive tissues (adrenal cortex, ovary, endometrium, prostate, and pituitary). Apocrine epithelium within axillary skin exhibited strongly positive staining for APO-D, and peripheral nerves, pituitary and renal tubules were also immunoreactive. Expression of Apo-D in the non-malignant prostate gland has not been reported. In paraffin-embedded tissues, Apo-D demonstrates a cytoplasmic staining pattern in some prostate carcinomas.
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length protein (Human).

  • 阳性对照
    • Prostate carcinoma tissue lysate.
  • 常规说明


    Apolipoprotein-D (APO-D), a progesterone binding glycoprotein of 24,000 dalton monomer molecular size, is a constituent of high density lipoprotein in plasma, and was first isolated in large quantity as GCDFP- 24, the major protein component of most human breast cyst fluids. In recent studies, Apo-D immunoreactivity has been shown to be an early indicator of prostate cancer and advanced primary prostate tumors.

性能

应用

Our Abpromise guarantee covers the use of ab10336 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/40. Retrieve antigens with 70% Formic acid for 10-30 minutes at room temperature before commencing with IHC staining protocol.

靶标

  • 功能APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.
  • 组织特异性Expressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears.
  • 序列相似性Belongs to the calycin superfamily. Lipocalin family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • APO D antibody
    • Apo-D antibody
    • ApoD antibody
    • APOD protein antibody
    • APOD_HUMAN antibody
    • Apolipoprotein D antibody
    • ApolipoproteinD antibody
    see all

Anti-Apolipoprotein D antibody [8CD6] 图像

  • IHC-P using Ab10336.

Anti-Apolipoprotein D antibody [8CD6] (ab10336)参考文献

This product has been referenced in:
  • Labrie M  et al. Apolipoprotein D Transgenic Mice Develop Hepatic Steatosis through Activation of PPAR? and Fatty Acid Uptake. PLoS One 10:e0130230 (2015). Read more (PubMed: 26083030) »

See 1 Publication for this product

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