重组
RabMAb

Anti-Apolipoprotein CIII抗体[EPR1371(2)] (ab108205)

概述

  • 产品名称
    Anti-Apolipoprotein CIII抗体[EPR1371(2)]
    参阅全部 Apolipoprotein CIII 一抗
  • 描述
    兔单克隆抗体[EPR1371(2)] to Apolipoprotein CIII
  • 经测试应用
    适用于: WB, IHC-Pmore details
    不适用于: Flow Cyt,ICC or IP
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (Human)

  • 阳性对照
    • WB: lysate from Human plasma or HDL cells; IHC-P: Human liver tissue.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

性能

应用

Our Abpromise guarantee covers the use of ab108205 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 11 kDa.
IHC-P 1/250 - 1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Heat up to 98 degrees C, below boiling, and then let cool for 10-20 min.
  • 应用说明
    Is unsuitable for Flow Cyt,ICC or IP.
  • 靶标

    • 功能
      Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles.
    • 组织特异性
      Constitutes 50% of the protein fraction of VLDL and 2% of that of HDL. Synthesized predominantly in liver and to a lesser degree in intestine.
    • 疾病相关
      Defects in APOC3 may be a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
    • 序列相似性
      Belongs to the apolipoprotein C3 family.
    • 翻译后修饰
      O-linked glycan consists of Gal-GalNAc disaccharide, further modified with up to 3 sialic acid residues. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan.
    • 细胞定位
      Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • APOC3 antibody
      • APO C3 antibody
      • Apo CIII antibody
      • Apo-CIII antibody
      • APOC 3 antibody
      • ApoC III antibody
      • ApoC-III antibody
      • APOC3 antibody
      • APOC3_HUMAN antibody
      • ApoCIII antibody
      • Apolipoprotein C III antibody
      • Apolipoprotein C-III antibody
      • Apolipoprotein C3 antibody
      • ApolipoproteinCIII antibody
      • MGC150353 antibody
      see all

    图片

    • All lanes : Anti-Apolipoprotein CIII antibody [EPR1371(2)] (ab108205) at 1/1000 dilution

      Lane 1 : Human plasma
      Lane 2 : HDL cell lysates

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 11 kDa
    • ab108205 at 1/250 dilution staining Apolipoprotein CIII in paraffin-embedded Human liver tissue by immunohistochemistry,.

    文献

    ab108205 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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