RabMAb

Anti-Apolipoprotein CIII抗体[EPR1371(2)] (ab108205)

概述

  • 产品名称Anti-Apolipoprotein CIII抗体[EPR1371(2)]
    参阅全部 Apolipoprotein CIII 一抗
  • 描述
    兔单克隆抗体[EPR1371(2)] to Apolipoprotein CIII
  • 经测试应用适用于: WB, IHC-Pmore details
    不适用于: Flow Cyt,ICC or IP
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (Human)

  • 阳性对照
    • WB: lysate from Human plasma or HDL cells; IHC-P: Human liver tissue.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab108205 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 11 kDa.
IHC-P 1/250 - 1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Heat up to 98 degrees C, below boiling, and then let cool for 10-20 min.
  • 应用说明Is unsuitable for Flow Cyt,ICC or IP.
  • 靶标

    • 功能Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles.
    • 组织特异性Constitutes 50% of the protein fraction of VLDL and 2% of that of HDL. Synthesized predominantly in liver and to a lesser degree in intestine.
    • 疾病相关Defects in APOC3 may be a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
    • 序列相似性Belongs to the apolipoprotein C3 family.
    • 翻译后修饰O-linked glycan consists of Gal-GalNAc disaccharide, further modified with up to 3 sialic acid residues. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • APOC3 antibody
      • APO C3 antibody
      • Apo CIII antibody
      • Apo-CIII antibody
      • APOC 3 antibody
      • ApoC III antibody
      • ApoC-III antibody
      • APOC3 antibody
      • APOC3_HUMAN antibody
      • ApoCIII antibody
      • Apolipoprotein C III antibody
      • Apolipoprotein C-III antibody
      • Apolipoprotein C3 antibody
      • ApolipoproteinCIII antibody
      • MGC150353 antibody
      see all

    Anti-Apolipoprotein CIII antibody [EPR1371(2)] 图像

    • All lanes : Anti-Apolipoprotein CIII antibody [EPR1371(2)] (ab108205) at 1/1000 dilution

      Lane 1 : Human plasma
      Lane 2 : HDL cell lysates

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 11 kDa
    • ab108205 at 1/250 dilution staining Apolipoprotein CIII in paraffin-embedded Human liver tissue by immunohistochemistry,.

    Anti-Apolipoprotein CIII antibody [EPR1371(2)] (ab108205)参考文献

    ab108205 has not yet been referenced specifically in any publications.

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