Anti-Apolipoprotein CIII抗体- Aminoterminal end (ab55984)


  • 产品名称
    Anti-Apolipoprotein CIII抗体- Aminoterminal end
    参阅全部 Apolipoprotein CIII 一抗
  • 描述
    兔多克隆抗体to Apolipoprotein CIII - Aminoterminal end
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Synthetic peptide corresponding to N-terminal residues of mouse Apolipoprotein CIII



Our Abpromise guarantee covers the use of ab55984 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
  • 应用说明
    ELISA: Use at an assay dependent dilution.
    WB: Use at an assay dependent concentration. Predicted molecular weight: 11 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles.
    • 组织特异性
      Constitutes 50% of the protein fraction of VLDL and 2% of that of HDL. Synthesized predominantly in liver and to a lesser degree in intestine.
    • 疾病相关
      Defects in APOC3 may be a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
    • 序列相似性
      Belongs to the apolipoprotein C3 family.
    • 翻译后修饰
      O-linked glycan consists of Gal-GalNAc disaccharide, further modified with up to 3 sialic acid residues. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan.
    • 细胞定位
    • Information by UniProt
    • 数据库链接
    • 别名
      • APOC3 antibody
      • APO C3 antibody
      • Apo CIII antibody
      • Apo-CIII antibody
      • APOC 3 antibody
      • ApoC III antibody
      • ApoC-III antibody
      • APOC3 antibody
      • APOC3_HUMAN antibody
      • ApoCIII antibody
      • Apolipoprotein C III antibody
      • Apolipoprotein C-III antibody
      • Apolipoprotein C3 antibody
      • ApolipoproteinCIII antibody
      • MGC150353 antibody
      see all


    Anti-Apolipoprotein CIII antibody - Aminoterminal end (ab55984)参考文献

    This product has been referenced in:
    • Johnson LA  et al. Apolipoprotein E4 Exaggerates Diabetic Dyslipidemia and Atherosclerosis in Mice Lacking the LDL Receptor. Diabetes 60:2285-94 (2011). ELISA ; Mouse . Read more (PubMed: 21810592) »
    • Kawakami A  et al. Apolipoprotein CIII links hyperlipidemia with vascular endothelial cell dysfunction. Circulation 118:731-42 (2008). WB ; Human . Read more (PubMed: 18663085) »

    See all 2 Publications for this product

    Product Wall

    Thank you for contacting us. We currently only have a mouse ELISA kit for Apolipoprotein CIII: ab108811 However, we do have antibodies to each of your targets of interest that can be used in ELISA on mouse samples: Apolipoprotein A I: ab7614 or ab20453...

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    Thank you for contacting us. Thank you for contacting us. The Anti-Apolipoprotein CIII antibody ab55984 is not exatcly the same as that supplied with the Apolipoprotein CIII Rat/Mouse ELISA Kit (ab108811). The kit uses an antibody directed towards ...

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    Thank you for your enquiry. ApoC3 is a protein in the liver. A mature apoC3 protein show a molecular mass of ~ 8.8 kDa, but it is sensitive to Thrombin cleavage, in this case, apoC3 results in two small fragment, a n-terminal fragement: residues 1 t...

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    Thank you for your enquiry. In normolipidaemic individuals, the total plasma ApoCIII level is 0.10 g/l which is mainly HDL-linked. Unfortunately, I am not sure about the level of plasma apoCIII in mice, but I guess it may not be a big difference. ...

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    Thank you for your enquiry. I can confirm that for WB, over-expressed cell lysate of Apolipoprotein CIII were used at 5ug per lane and the dilution of the antibody is about 1ug/ml. Unfortunately, we do not have any information on the ELISA positive ...

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