Anti-Apolipoprotein CIII抗体(ab124256)

概述

  • 产品名称Anti-Apolipoprotein CIII抗体
    参阅全部 Apolipoprotein CIII 一抗
  • 描述
    山羊多克隆抗体to Apolipoprotein CIII
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human Apo CIII recombinant protein corresponds to N-terminal 99 amino acids

  • 阳性对照
    • Human liver tissue.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab124256 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2500 - 1/20000. Predicted molecular weight: 11 kDa.
IHC-P Use a concentration of 5 µg/ml.

靶标

  • 功能Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles.
  • 组织特异性Constitutes 50% of the protein fraction of VLDL and 2% of that of HDL. Synthesized predominantly in liver and to a lesser degree in intestine.
  • 疾病相关Defects in APOC3 may be a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
  • 序列相似性Belongs to the apolipoprotein C3 family.
  • 翻译后修饰O-linked glycan consists of Gal-GalNAc disaccharide, further modified with up to 3 sialic acid residues. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • APOC3 antibody
    • APO C3 antibody
    • Apo CIII antibody
    • Apo-CIII antibody
    • APOC 3 antibody
    • ApoC III antibody
    • ApoC-III antibody
    • APOC3 antibody
    • APOC3_HUMAN antibody
    • ApoCIII antibody
    • Apolipoprotein C III antibody
    • Apolipoprotein C-III antibody
    • Apolipoprotein C3 antibody
    • ApolipoproteinCIII antibody
    • MGC150353 antibody
    see all

Anti-Apolipoprotein CIII antibody 图像

  • ab124256 at 5 µg/ml, staining Apolipoprotein CIII in Formalin-Fixed Human Liver by immunohistochemistry.

Anti-Apolipoprotein CIII antibody (ab124256)参考文献

ab124256 has not yet been referenced specifically in any publications.

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