The antibody can be used to detect human Apolipoprotein CIII in plasma, immunoassays and immunoblots.
1/200 - 1/8000.
Appears to modulate the interaction of APOE with beta-migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification.
Synthesized mainly in liver and to a minor degree in intestine. Secreted in plasma.
Dernick G et al. Multidimensional profiling of plasma lipoproteins by size exclusion chromatography followed by reverse-phase protein arrays. J Lipid Res52:2323-31 (2011).
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