FITC荧光Anti-Apolipoprotein B抗体(ab27637)
Key features and details
- FITC Goat polyclonal to Apolipoprotein B
- Suitable for: ICC/IF
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
概述
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产品名称
FITC荧光Anti-Apolipoprotein B抗体
参阅全部 Apolipoprotein B 一抗 -
描述
FITC荧光山羊多克隆抗体to Apolipoprotein B -
宿主
Goat -
偶联物
FITC. Ex: 493nm, Em: 528nm -
特异性
This antibody is specific for human apo B-100 (apolipoprotein B). -
经测试应用
适用于: ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
Full length native LDL protein (purified)
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常规说明
Molar F/P ratio is 6.1.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 0.2% PBS, 0.0146% EDTA, 0.435% Sodium chloride, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
Purified by human apo B-100-Sepharose™ affinity column. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab27637于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ICC/IF |
Use at an assay dependent concentration.
|
说明 |
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ICC/IF
Use at an assay dependent concentration. |
靶标
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功能
Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. -
疾病相关
Hypobetalipoproteinemia, familial, 1
Familial ligand-defective apolipoprotein B-100
Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia. -
序列相似性
Contains 1 vitellogenin domain. -
翻译后修饰
Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle. -
细胞定位
Cytoplasm. Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 338 Human
- Omim: 107730 Human
- SwissProt: P04114 Human
- Unigene: 120759 Human
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别名
- Apo B 100 antibody
- Apo B antibody
- Apo B-100 antibody
see all
数据表及文件
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Datasheet download
文献 (3)
ab27637 被引用在 3 文献中.
- Chetty VK et al. Efficient Small Extracellular Vesicles (EV) Isolation Method and Evaluation of EV-Associated DNA Role in Cell-Cell Communication in Cancer. Cancers (Basel) 14:N/A (2022). PubMed: 35565197
- Zhou J et al. High-throughput single-EV liquid biopsy: Rapid, simultaneous, and multiplexed detection of nucleic acids, proteins, and their combinations. Sci Adv 6:N/A (2020). PubMed: 33219024
- Pang B et al. Quality Assessment and Comparison of Plasma-Derived Extracellular Vesicles Separated by Three Commercial Kits for Prostate Cancer Diagnosis. Int J Nanomedicine 15:10241-10256 (2020). PubMed: 33364756