Anti-Apelin抗体(ab125213)

概述

  • 产品名称Anti-Apelin抗体
    参阅全部 Apelin 一抗
  • 描述
    兔多克隆抗体to Apelin
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide from the C terminal region of Human Apelin.

  • 阳性对照
    • U87, MCF7, HeLa, MM453 whole cell lysates.

性能

应用

Our Abpromise guarantee covers the use of ab125213 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 9 kDa. The detection limit for ab125213 is approximately 1ng/lane under non-reducing and reducing conditions.

靶标

  • 功能Endogenous ligand for APJ, an alternative coreceptor with CD4 for HIV-1 infection. Inhibits HIV-1 entry in cells coexpressing CD4 and APJ. Apelin-36 has a greater inhibitory activity on HIV infection than other synthetic apelin derivatives. The oral intake in the colostrum and the milk could have a role in the modulation of the immune responses in neonates. May also have a role in the central control of body fluid homeostasis by influencing AVP release and drinking behavior.
  • 组织特异性Expressed in the brain with highest levels in the frontal cortex, thalamus, hypothalamus and midbrain. Secreted by the mammary gland into the colostrum and the milk.
  • 序列相似性Belongs to the apelin family.
  • 翻译后修饰Several active peptides may be produced by proteolytic processing of the peptide precursor.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AGTRL1 ligand antibody
    • APEL antibody
    • APEL_HUMAN antibody
    • Apelin-13 antibody
    • APJ endogenous ligand antibody
    • Apln antibody
    • XNPEP2 antibody
    see all

Anti-Apelin antibody 图像

  • All lanes : Anti-Apelin antibody (ab125213) at 0.5 µg/ml

    Lane 1 : U87 Cell lysate
    Lane 2 : MCF-7 Cell Lysate
    Lane 3 : HELA Cell Lysate
    Lane 4 : MM453 Cell lysate

    Lysates/proteins at 40 µg per lane.


    Predicted band size : 9 kDa

Anti-Apelin antibody (ab125213)参考文献

ab125213 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample Rat Tissue sections (Lung section)
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Sodium citrate buffer
Permeabilization No
Specification Lung section
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Fixative Formaldehyde
Username

Amreen Mughal

Verified customer

提交于 Mar 15 2017

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"