概述

  • 产品名称Anti-Apc5抗体
    参阅全部 Apc5 一抗
  • 描述
    兔多克隆抗体to Apc5
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide conjugated to KLH derived from an internal sequence of Human Apc5.

  • 阳性对照
    • Human Small Intestine and Human Placenta tissues, Human kidney tissue lysate

性能

应用

Our Abpromise guarantee covers the use of ab113359 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 85 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Belongs to the APC5 family.
    Contains 4 TPR repeats.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2510006G12Rik antibody
    • AA408751 antibody
    • AA536819 antibody
    • AA986414 antibody
    • ANAPC 5 antibody
    • ANAPC5 antibody
    • Anaphase promoting complex subunit 5 antibody
    • Anaphase-promoting complex subunit 5 antibody
    • Apc 5 antibody
    • APC5 antibody
    • APC5_HUMAN antibody
    • Cyclosome subunit 5 antibody
    • PDL 108 antibody
    • PDL108 antibody
    • Periodontal ligament fibroblast protein antibody
    • RMC1 antibody
    see all

Anti-Apc5 antibody 图像

  • Lane 1 : Anti-Apc5 antibody (ab113359) at 1 µg/ml
    Lane 2 : Anti-Apc5 antibody (ab113359) at 2 µg/ml

    Lane 1 : Human kidney tissue lysate
    Lane 2 : Human kidney tissue lysate


    Predicted band size : 85 kDa
  • Staining of Human Apc5 in a Formalin/PFA-fixed paraffin-embedded section of Human Small Intestine using ab113359 at a concentration of 5 µg/ml.
  • Staining of Human Apc5 in a Formalin/PFA-fixed paraffin-embedded section of Human Placenta using ab113359 at a concentration of 5 µg/ml.

Anti-Apc5 antibody (ab113359)参考文献

ab113359 has not yet been referenced specifically in any publications.

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