概述

  • 产品名称Anti-Apc4抗体
    参阅全部 Apc4 一抗
  • 描述
    兔多克隆抗体to Apc4
  • 特异性ab106486 is predicted not to cross-react with other APC family members. At least two isoforms of Apc4 are known to exist.
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A 14 amino acid synthetic peptide near the N terminus of Human Apc4 (UniProt Q9UJX5).

  • 阳性对照
    • Mouse liver tissue lysate; Rat liver tissue

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

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应用

Our Abpromise guarantee covers the use of ab106486 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 92 kDa.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Belongs to the APC4 family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ANAPC 4 antibody
    • anapc4 antibody
    • Anaphase Promoting Complex Subunit 4 antibody
    • Anaphase-promoting complex subunit 4 antibody
    • APC 4 antibody
    • APC Complex Protein CUT20 antibody
    • APC4 antibody
    • APC4_HUMAN antibody
    • CUT20 antibody
    • Cyclosome subunit 4 antibody
    • LID1 antibody
    see all

Anti-Apc4 antibody 图像

  • Lane 1 : Anti-Apc4 antibody (ab106486) at 1 µg/ml
    Lane 2 : Anti-Apc4 antibody (ab106486) at 2 µg/ml

    Lane 1 : Mouse liver tissue lysate
    Lane 2 : Mouse liver tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 92 kDa
  • ab106486, at 5 µg/ml, staining Apc4 in Rat liver tissue by Immunohistochemistry.

Anti-Apc4 antibody (ab106486)参考文献

ab106486 has not yet been referenced specifically in any publications.

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