概述

  • 产品名称Anti-APC2抗体
    参阅全部 APC2 一抗
  • 描述
    兔多克隆抗体to APC2
  • 经测试应用适用于: WB, ELISA, IHC-P, ICCmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids of Human APC2 (NP_005874.1).

  • 阳性对照
    • Human Brain Cortex and Small Intestine tissues; HeLa cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab113370 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 244 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.
ICC Use at an assay dependent concentration.

靶标

  • 相关性APC2 might function in the Wnt signaling pathway through it's ability to promote the rapid degradation of beta-catenin. It also functions as a tumour suppressor.
  • 细胞定位Cell Membrane, Cytoplasmic and Golgi Apparatus
  • 数据库链接
  • 别名
    • Adenomatous polyposis coli protein 2 antibody
    • Adenomatous polyposis coli protein-like antibody
    • APCL antibody

Anti-APC2 antibody 图像

  • ab113370, at 5 µg/ml, staining APC2 in Formalin-fixed, Paraffin-embedded Human Brain cortex tissue by Immunohistochemistry.
  • ab113370, at 5 µg/ml, staining APC2 in Formalin-fixed, Paraffin-embedded Human Small intestine tissue by Immunohistochemistry.
  • Lane 1 : Anti-APC2 antibody (ab113370) at 1 µg/ml
    Lane 2 : Anti-APC2 antibody (ab113370) at 2 µg/ml

    Lane 1 : HeLa cell lysate
    Lane 2 : HeLa cell lysate


    Predicted band size : 244 kDa

Anti-APC2 antibody (ab113370)参考文献

This product has been referenced in:
  • Hebert AM  et al. Merlin/ERM proteins establish cortical asymmetry and centrosome position. Genes Dev 26:2709-23 (2012). WB ; Human . Read more (PubMed: 23249734) »

See 1 Publication for this product

Product Wall

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (Small bowel)
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: EDTA pH8.5
Permeabilization No
Specification Small bowel
Blocking step Ventana blocking agent as blocking agent for 4 minute(s) · Concentration: 100% · Temperature: 36°C
Fixative Formaldehyde
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提交于 Sep 07 2015

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"