概述

  • 产品名称Anti-Apc2抗体
    参阅全部 Apc2 一抗
  • 描述
    兔多克隆抗体to Apc2
  • 特异性ab106600 is predicted to not cross-react with other Apc family members. At least four isoforms of Apc2 are known to exist.
  • 经测试应用适用于: ICC/IF, WB, ICCmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    18 amino acid peptide from near the center of Human Apc2 (BAA34611).

  • 阳性对照
    • HeLa cells and cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab106600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 244 kDa.
ICC Use a concentration of 5 µg/ml.

靶标

  • 功能Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Belongs to the cullin family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • anapc2 antibody
    • Anaphase promoting complex subunit 2 antibody
    • Anaphase-promoting complex subunit 2 antibody
    • ANC2_HUMAN antibody
    • APC2 antibody
    • Cyclosome subunit 2 antibody
    • KIAA1406 antibody
    • OTTHUMP00000022692 antibody
    • RP11 350O14.5 antibody
    see all

Anti-Apc2 antibody 图像

  • Immunofluorescence of Apc2 in HeLa cells with ab106600 at 20 ug/mL.

  • Lane 1 : Anti-Apc2 antibody (ab106600) at 1 µg/ml
    Lane 2 : Anti-Apc2 antibody (ab106600) at 2 µg/ml

    Lane 1 : HeLa cell lysate
    Lane 2 : HeLa cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 244 kDa
  • Immunocytochemical analysis of ab106600 at 5 µg/ml in HeLa cells.

Anti-Apc2 antibody (ab106600)参考文献

ab106600 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab106600.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"