Anti-Apc11抗体[AX2.1] (ab78092)

概述

  • 产品名称Anti-Apc11抗体[AX2.1]
    参阅全部 Apc11 一抗
  • 描述
    小鼠单克隆抗体[AX2.1] to Apc11
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human, Xenopus laevis
  • 免疫原

    Synthetic peptide spanning the carboxy region of APC11.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度IgG fraction
  • 克隆单克隆
  • 克隆编号AX2.1
  • 骨髓瘤Sp2/0-Ag14
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab78092 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 10 kDa.

靶标

  • 功能Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
  • 组织特异性Expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, and liver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Belongs to the RING-box family.
    Contains 1 RING-type zinc finger.
  • 结构域The RING-type zinc finger domain coordinates an additional third zinc ion.
  • 翻译后修饰Auto-ubiquitinated.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ANAPC 11 antibody
    • ANAPC11 antibody
    • Anaphase promoting complex subunit 11 (yeast APC11 homolog) antibody
    • Anaphase promoting complex subunit 11 antibody
    • Anaphase promoting complex subunit 11 homolog (yeast) antibody
    • Anaphase promoting complex subunit 11 homolog antibody
    • Anaphase-promoting complex subunit 11 antibody
    • Apc 11 antibody
    • Apc 11p antibody
    • APC11 anaphase promoting complex subunit 11 homolog (yeast) antibody
    • APC11 anaphase promoting complex subunit 11 homolog antibody
    • APC11 antibody
    • APC11_HUMAN antibody
    • Apc11p antibody
    • Cyclosome subunit 11 antibody
    • Hepatocellular carcinoma associated RING finger protein antibody
    • Hepatocellular carcinoma-associated RING finger protein antibody
    • HSPC 214 antibody
    • HSPC214 antibody
    • MGC882 antibody
    • Yeast APC 11 homolog antibody
    • Yeast APC11 homolog antibody
    see all

Anti-Apc11 antibody [AX2.1] (ab78092)参考文献

ab78092 has not yet been referenced specifically in any publications.

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