• 产品名称
  • 描述
    兔多克隆抗体to Apc11
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Full length protein corresponding to Human Apc11.

  • 阳性对照
    • HeLa, NIH-3T3 cells


  • 形式
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    pH: 7.40
    Preservative: 0.1% Sodium azide
    Constituent: 0.01% PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 克隆
  • 同种型
  • 研究领域


Our Abpromise guarantee covers the use of ab44708 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/400. Predicted molecular weight: 10 kDa.


  • 功能
    Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
  • 组织特异性
    Expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, and liver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte.
  • 通路
    Protein modification; protein ubiquitination.
  • 序列相似性
    Belongs to the RING-box family.
    Contains 1 RING-type zinc finger.
  • 结构域
    The RING-type zinc finger domain coordinates an additional third zinc ion.
  • 翻译后修饰
  • 细胞定位
    Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ANAPC 11 antibody
    • ANAPC11 antibody
    • Anaphase promoting complex subunit 11 (yeast APC11 homolog) antibody
    • Anaphase promoting complex subunit 11 antibody
    • Anaphase promoting complex subunit 11 homolog (yeast) antibody
    • Anaphase promoting complex subunit 11 homolog antibody
    • Anaphase-promoting complex subunit 11 antibody
    • Apc 11 antibody
    • Apc 11p antibody
    • APC11 anaphase promoting complex subunit 11 homolog (yeast) antibody
    • APC11 anaphase promoting complex subunit 11 homolog antibody
    • APC11 antibody
    • APC11_HUMAN antibody
    • Apc11p antibody
    • Cyclosome subunit 11 antibody
    • Hepatocellular carcinoma associated RING finger protein antibody
    • Hepatocellular carcinoma-associated RING finger protein antibody
    • HSPC 214 antibody
    • HSPC214 antibody
    • MGC882 antibody
    • Yeast APC 11 homolog antibody
    • Yeast APC11 homolog antibody
    see all


Anti-Apc11 antibody (ab44708)参考文献

ab44708 has not yet been referenced specifically in any publications.

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