概述

  • 产品名称
    APBA1肽

描述

  • 性质
    Synthetic

相关产品

技术指标

Our Abpromise guarantee covers the use of ab4980 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式
    Liquid
  • 补充说明


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat Mint 1, catalog ab3448. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

常规信息

  • 别名
    • Adapter protein X11 alpha
    • Adapter protein X11alpha
    • Amyloid beta A4 precursor protein-binding family A member 1
    • Apba1
    • APBA1_HUMAN
    • Mint 1
    • Mint-1
    • Neuron specific X11 protein
    • Neuron-specific X11 protein
    • Neuronal Munc18 1 interacting protein 1
    • Neuronal Munc18-1-interacting protein 1
    • UROP11
    • x11
    • X11alpha
    see all
  • 功能
    Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.
  • 组织特异性
    Brain and spinal cord.
  • 序列相似性
    Contains 2 PDZ (DHR) domains.
    Contains 1 PID domain.
  • 结构域
    Composed of an N-terminal domain that binds Munc18-1 and LIN-2/CASK, a middle phosphotyrosine-binding domain (PID/PTB) that mediates binding with the cytoplasmic domain of the beta-amyloid precursor protein, and two C-terminal PDZ domains thought to attach proteins to the plasma membrane.
  • Information by UniProt

文献

ab4980 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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