概述

  • 产品名称Anti-AP4E1抗体
    参阅全部 AP4E1 一抗
  • 描述
    兔多克隆抗体to AP4E1
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence, corresponding to amino acids 306-408 of Human AP4E1.

  • 阳性对照
    • Human small intestine tissue.

性能

应用

Our Abpromise guarantee covers the use of ab122753 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
  • 组织特异性Widely expressed.
  • 疾病相关Defects in AP4E1 are the cause of cerebral palsy spastic quadriplegic type 4 (CPSQ4) [MIM:613744]. A non-progressive disorder of movement and/or posture resulting from defects in the developing central nervous system. Affected individuals manifest motor and posture impairments often associated with epilepsy and disturbances of cognition, behavior, sensation, and communication.
  • 序列相似性Belongs to the adaptor complexes large subunit family.
  • 细胞定位Golgi apparatus > trans-Golgi network. Associated with the trans-Golgi network. Found in soma and dendritic shafts of neuronal cells.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Adapter-related protein complex 4 subunit epsilon-1 antibody
    • Adaptor related protein complex 4 epsilon 1 subunit antibody
    • Adaptor related protein complex AP 4 epsilon antibody
    • AP-4 adapter complex subunit epsilon antibody
    • AP-4 complex subunit epsilon-1 antibody
    • Ap4e1 antibody
    • AP4E1_HUMAN antibody
    • CPSQ4 antibody
    • Epsilon subunit of AP-4 antibody
    • Epsilon-adaptin antibody
    see all

Anti-AP4E1 antibody 图像

  • ab122753 at 1/50 dilution, staining AP4E1 in Paraffin-embedded Human small intestine tissue by Immunohistochemistry.

Anti-AP4E1 antibody (ab122753)参考文献

ab122753 has not yet been referenced specifically in any publications.

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