概述

  • 产品名称
  • 描述
    鸡多克隆抗体to AP3B2
  • 经测试应用
    适用于: ICCmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide:

    SLLEENAEK AFYGSEEDEA KGAGSEETAA AAAPSRKPYV MDPDHRLLLR NTKPLLQSRSA AVVMAVAQLYFH LAPKAEVGVIAK ALVRLLRS

    , corresponding to amino acids 259-350 of Human AP3B2.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgY
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab14227 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC 1/200.

靶标

  • 功能
    Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles.
  • 组织特异性
    Expression is specific to nervous system. Expressed in nerve terminal and cell body, and is associated with nerve-terminal vesicles. Expression seen in Purkinje cells, cortical neurons, neuroectodermal tumors and graded in cerebral cortex (deeper layers exhibit stronger expression).
  • 序列相似性
    Belongs to the adaptor complexes large subunit family.
  • 发展阶段
    Expressed from early in development through adulthood.
  • 细胞定位
    Golgi apparatus. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Golgi apparatus. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Adapter-related protein complex 3 subunit beta-2 antibody
    • Adaptor protein complex AP-3 subunit beta-2 antibody
    • Adaptor related protein complex 3 beta 2 subunit antibody
    • AP 3 complex subunit beta 2 antibody
    • AP-3 complex subunit beta-2 antibody
    • AP3B2 antibody
    • AP3B2_HUMAN antibody
    • beta NAP antibody
    • Beta-3B-adaptin antibody
    • Beta3B adaptin antibody
    • Beta3b antibody
    • Clathrin assembly protein complex 3 beta 2 large chain antibody
    • Clathrin assembly protein complex 3 beta-2 large chain antibody
    • NAPTB antibody
    • Neuron specific vesicle coat protein and cerebellar degeneration antigen antibody
    • Neuron-specific vesicle coat protein beta-NAP antibody
    • Neuronal adaptin like protein beta subunit antibody
    see all

图片

  • Immunocytochemistry staining of endogenous AP3B2 in AtT-20 cells. ab14227 dilution: 1/200; Donkey anti-IgY Fc-FITC: 1/200.

文献

ab14227 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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