概述

  • 产品名称Anti-AP3B2抗体
    参阅全部 AP3B2 一抗
  • 描述
    兔多克隆抗体to AP3B2
  • 特异性At least three isoforms of AP3B2 are known to exist; this antibody will recognize the two larger isoforms.
  • 经测试应用适用于: WB, ICC/IF, ICC, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    An 18 amino acid synthetic peptide from near the amino terminus of Human AP3B2 (NP_004635).

  • 阳性对照
    • Rat brain tissue. Mouse brain tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • 存储溶液Preservative: 0.02% Sodium azide
    Constituent: 99.98% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab113100 is purified by affinity chromatography via a peptide column.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab113100 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 119 kDa.
ICC/IF Use a concentration of 20 µg/ml.
ICC Use a concentration of 5 µg/ml.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles.
  • 组织特异性Expression is specific to nervous system. Expressed in nerve terminal and cell body, and is associated with nerve-terminal vesicles. Expression seen in Purkinje cells, cortical neurons, neuroectodermal tumors and graded in cerebral cortex (deeper layers exhibit stronger expression).
  • 序列相似性Belongs to the adaptor complexes large subunit family.
  • 发展阶段Expressed from early in development through adulthood.
  • 细胞定位Golgi apparatus. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Golgi apparatus. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Adapter-related protein complex 3 subunit beta-2 antibody
    • Adaptor protein complex AP-3 subunit beta-2 antibody
    • Adaptor related protein complex 3 beta 2 subunit antibody
    • AP 3 complex subunit beta 2 antibody
    • AP-3 complex subunit beta-2 antibody
    • AP3B2 antibody
    • AP3B2_HUMAN antibody
    • beta NAP antibody
    • Beta-3B-adaptin antibody
    • Beta3B adaptin antibody
    • Beta3b antibody
    • Clathrin assembly protein complex 3 beta 2 large chain antibody
    • Clathrin assembly protein complex 3 beta-2 large chain antibody
    • NAPTB antibody
    • Neuron specific vesicle coat protein and cerebellar degeneration antigen antibody
    • Neuron-specific vesicle coat protein beta-NAP antibody
    • Neuronal adaptin like protein beta subunit antibody
    see all

Anti-AP3B2 antibody 图像

  • Immunofluorescence of AP3B2 in mouse brain tissue with ab113100 at 20 ug/mL.
  • Lane 1 : Anti-AP3B2 antibody (ab113100) at 1 µg/ml
    Lane 2 : Anti-AP3B2 antibody (ab113100) at 2 µg/ml

    Lane 1 : Rat brain tissue lysate
    Lane 2 : Rat brain tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 119 kDa
  • Immunohistochemical analysis of mouse brain tissue, staining AP3B2 with ab113100 at 5 µg/ml.

Anti-AP3B2 antibody (ab113100)参考文献

ab113100 has not yet been referenced specifically in any publications.

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