The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500. Detects a band of approximately 130 kDa (predicted molecular weight: 130 kDa).
功能Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.
组织特异性Present in all adult tissues examined with the highest levels in skeletal muscle, heart, pancreas and testis.
序列相似性Belongs to the adaptor complexes large subunit family. Contains 11 HEAT repeats.