概述

  • 产品名称Anti-AP2 alpha + beta抗体
    参阅全部 AP2 alpha + beta 一抗
  • 描述
    兔多克隆抗体to AP2 alpha + beta
  • 特异性This antibody recognizes both AP2 alpha A (50 kDa) and AP2 alpha B (40 kDa) forms of AP2.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Sheep, Chicken, Xenopus laevis
  • 免疫原

    Synthetic peptide:

    GLDPRRDYRRHEDLL

    , corresponding to amino acids 120-134 of Human AP2 alpha + beta.

  • 阳性对照
    • JEG-3 nuclear extract.
  • 常规说明


    The AP2 transcription factors form the OB2 complex that has been shown to up-regulate c-erbB-2 transcription.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.1% Sodium Azide and 0.01% Thiomerosal.
    Constituents: PBS containing 0.2% Gelatin.
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • Primary antibody说明The AP2 transcription factors form the OB2 complex that has been shown to up-regulate c-erbB-2 transcription.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

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应用

Our Abpromise guarantee covers the use of ab11907 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 40, 50 kDa (predicted molecular weight: a=40, b=50 kDa).

靶标

  • 相关性The AP2 proteins are normally expressed in ectodermally derived vertebrate tissues where they are necessary for normal growth and development. The factors have also been implicated in the control of cell proliferation, viral transformation, and oncogenesis. AP2 seems to play in important role in human breast cancer. AP2 alpha is the only AP2 protein required for early morphogenesis of the lens vesicle. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia
  • 细胞定位Nuclear
  • 数据库链接
  • 别名
    • Activating enhancer binding protein 2 alpha antibody
    • Activating enhancer binding protein 2 beta antibody
    • Activator protein 2 antibody
    • AP 2 antibody
    • AP 2alpha antibody
    • AP 2B antibody
    • AP-2 transcription factor antibody
    • AP2 B antibody
    • AP2-alpha antibody
    • AP2-beta antibody
    • AP2TF antibody
    • BOFS antibody
    • TFAP2 antibody
    • TFAP2A antibody
    • TFAP2B antibody
    • Transcription factor AP2 alpha antibody
    • Transcription factor AP2 beta antibody
    see all

Anti-AP2 alpha + beta antibody 图像



  • Predicted band size : a=40, b=50 kDa


    Detection of AP2 by Western blot analysis. Activator protein 2 (AP2) can be detected in nuclear extracts derived from JEG-3 cells using AP2 rabbit polyclonal antibody at a 1/1000 dilution (lane 1). The signal corresponding to nuclear AP2 is eliminated by adding the immunizing peptide to the reaction (lane 2).

Anti-AP2 alpha + beta antibody (ab11907)参考文献

This product has been referenced in:
  • Terrand J  et al. LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling. J Biol Chem 284:381-8 (2009). WB ; Mouse . Read more (PubMed: 18990694) »

See 1 Publication for this product

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