概述

  • 产品名称Anti-AP1S2抗体
  • 描述
    兔多克隆抗体to AP1S2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Cow, Zebrafish
  • 免疫原

    Recombinant fragment containing a sequence corresponding to a region within amino acids 1-122 of Human AP1S2 (NP_003907).

  • 阳性对照
    • Raji whole cell lysate; A431 cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab97590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 19 kDa.

靶标

  • 功能Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
  • 组织特异性Widely expressed.
  • 疾病相关Defects in AP1S2 are the cause of mental retardation X-linked type 59 (MRX59) [MIM:300630]. It is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. In contrast to syndromic or specific X-linked mental retardation which also present with associated physical, neurological and/or psychiatric manifestations, intellectual deficiency is the only primary symptom of non-syndromic X-linked mental retardation. MRX59 consists of a mild-to-profound mental retardation. Other features includes hypotonia early in life and delay in walking.
  • 序列相似性Belongs to the adaptor complexes small subunit family.
  • 细胞定位Golgi apparatus. Cytoplasmic vesicle membrane. Membrane > clathrin-coated pit. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Adapter related protein complex 1 sigma 1B subunit antibody
    • Adapter-related protein complex 1 sigma-1B subunit antibody
    • Adaptor protein complex AP 1 sigma 1B subunit antibody
    • Adaptor protein complex AP-1 sigma-1B subunit antibody
    • Adaptor related protein complex 1 sigma 2 subunit antibody
    • AP 1 complex subunit sigma 2 antibody
    • AP-1 complex subunit sigma-2 antibody
    • ap1s2 antibody
    • AP1S2_HUMAN antibody
    • Clathrin adaptor complex AP1 sigma 1B subunit antibody
    • Clathrin assembly protein complex 1 sigma 1B small chain antibody
    • Clathrin assembly protein complex 1 sigma-1B small chain antibody
    • Clathrin associated assembly adaptor protein small 1 like antibody
    • DC22 antibody
    • Golgi adaptor HA1 AP1 adaptin sigma 1B subunit antibody
    • Golgi adaptor HA1/AP1 adaptin sigma-1B subunit antibody
    • mental retardation X linked 59 antibody
    • MGC:1902 antibody
    • MRX59 antibody
    • Sigma 1B subunit of AP 1 clathrin antibody
    • Sigma 1B subunit of AP-1 clathrin antibody
    • Sigma adaptin 1B antibody
    • Sigma-adaptin 1B antibody
    • Sigma1B adaptin antibody
    • SIGMA1B antibody
    • Sigma1B-adaptin antibody
    see all

Anti-AP1S2 antibody 图像

  • Anti-AP1S2 antibody (ab97590) at 1/1000 dilution + Raji whole cell lysate at 30 µg

    Predicted band size : 19 kDa

Anti-AP1S2 antibody (ab97590)参考文献

ab97590 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab97590.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"