概述

  • 产品名称
  • 描述
    兔多克隆抗体to AP1M1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 206-235 of Human AP1M1 (NP_115882.1).

  • 阳性对照
    • A375 cell line lysate

性能

应用

Our Abpromise guarantee covers the use of ab111135 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 49 kDa.

靶标

  • 功能
    Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
  • 序列相似性
    Belongs to the adaptor complexes medium subunit family.
    Contains 1 MHD (mu homology) domain.
  • 翻译后修饰
    Phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals.
  • 细胞定位
    Golgi apparatus. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Adaptor protein complex AP-1 mu-1 subunit antibody
    • Adaptor-related protein complex 1 mu-1 subunit antibody
    • AP-1 complex subunit mu-1 antibody
    • AP-mu chain family member mu1A antibody
    • Ap1m1 antibody
    • AP1M1_HUMAN antibody
    • AP47 antibody
    • CLAPM2 antibody
    • Clathrin adaptor protein AP47 antibody
    • Clathrin assembly protein complex 1 medium chain 1 antibody
    • Clathrin assembly protein complex 1 medium chain antibody
    • Clathrin assembly protein complex AP1 mu subunit antibody
    • Clathrin coat assembly protein AP47 antibody
    • Clathrin coat-associated protein AP47 antibody
    • CLTNM antibody
    • Golgi adaptor AP 1 47 kDa protein antibody
    • Golgi adaptor HA1/AP1 adaptin mu-1 subunit antibody
    • HA1 47 kDa subunit antibody
    • MU 1A antibody
    • Mu-adaptin 1 antibody
    • Mu1A-adaptin antibody
    see all

图片

  • Anti-AP1M1 antibody (ab111135) at 1/100 dilution + A375 cell line lysate at 35 µg

    Predicted band size : 49 kDa

实验方案

文献

ab111135 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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