概述

  • 产品名称Anti-AOC2抗体
    参阅全部 AOC2 一抗
  • 描述
    兔多克隆抗体to AOC2
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide within residues: AEDIPNTVTL GNRVGFLLRP YNFFDEDPSI FSPGSVYFEK GQDAGLCSIN , corresponding to internal sequence amino acids 684-733 of Human AOC2 (NP_033720).

  • 阳性对照
    • Fetal lung lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab83734 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 84 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/1562500.

靶标

  • 功能Has a monoamine oxidase activity with substrate specificity for 2-phenylethylamine and tryptamine. May play a role in adipogenesis. May be a critical modulator of signal transmission in retina.
  • 组织特异性Expressed in many tissues with much higher expression in retina. Isoform 1 and isoform 2 are expressed in adipose tissue, whereas isoform 1 only seems to be present in thymus, and isoform 2 only in testis.
  • 序列相似性Belongs to the copper/topaquinone oxidase family.
  • 翻译后修饰Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
  • 细胞定位Cell membrane. Present on the surface of the cells and Cytoplasm. Either not translocated to the plasma membrane or below detection level.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Amine oxidase [copper containing] antibody
    • Amine oxidase [copper-containing] antibody
    • Amine oxidase copper containing 2 (retina specific) antibody
    • Amine oxidase copper containing 2 antibody
    • AOC2 antibody
    • AOC2_HUMAN antibody
    • DAO2 antibody
    • RAO antibody
    • Retina specific copper amine oxidase antibody
    • Retina-specific copper amine oxidase antibody
    • Semicarbazide-sensitive amine oxidase antibody
    • SSAO antibody
    see all

Anti-AOC2 antibody 图像

  • Anti-AOC2 antibody (ab83734) at 1 µg/ml (5% skim milk / PBS buffer) + Fetal lung lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 84 kDa
    Observed band size : 90 kDa (why is the actual band size different from the predicted?)

Anti-AOC2 antibody (ab83734)参考文献

ab83734 has not yet been referenced specifically in any publications.

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