Anti-Anthrax EF抗体(ab21267)

概述

  • 产品名称Anti-Anthrax EF抗体
  • 描述
    兔多克隆抗体to Anthrax EF
  • 经测试应用适用于: ELISAmore details
  • 种属反应性
    Reacts with Bacillus anthracis. Not yet tested in other species.
  • 免疫原

    Synthetic peptide corresponding to 16 amino acids near the carboxy terminus of Anthrax Edema Factor.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab21267 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use a concentration of 1 µg/ml. Note: at this concentration ab21267 will detect 10 ng of free peptide.

靶标

  • 相关性Anthrax infection is initiated by inhalation, ingestion or cutaneous contact with Bacillus anthracis endospores. B. anthracis produces three polypeptides that comprise the anthrax toxin: protective antigen (PA), lethal factor (LF) and edema factor (EF). PA binds to two related proteins on the cell surface; these are termed tumor epithelial marker 8 (TEM8)/anthrax toxin receptor (ATR) and capillary morphogenesis protein 2 (CMG2), although it is still unclear which is physiologically relevant. Following PA binding to its receptor, PA is cleaved into two fragments by a furin like protease. The bound fragment binds both LF and EF; the resulting complex is then endocytosed which allows the translocation of LF and EF into the cytoplasm. EF is a calmodulin and Ca++ dependent adenylate cyclase responsible for the edema seen in the disease. It is thought to benefit the B. anthracis bacteria by inhibiting cells of the host immune system.
  • 别名
    • Adenylyl cyclase antibody
    • Bacillus anthracis EF antibody
    • Cya antibody
    • Edema factor antibody
    • EF antibody
    see all

Anti-Anthrax EF antibody (ab21267)参考文献

ab21267 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry. Unfortunately, we do not have any anthrax PA antigen available in our catalog. I would like to recommend checking the Biocompare website which has an excellent antibody search facility that includes many suppliers. The...

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Thank you for contacting us. Our antibody ab21267 is against Anthrax EF, it is not an anti-Anthrax PA. We have a pair of antibodies anti-Anthrax PA for sELISA : - ab8240 that can be used as capture antibody - ab1990 that can be used as detect...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"