Anti-Annexin V抗体[1F4-1A5] (ab117439)

概述

  • 产品名称Anti-Annexin V抗体[1F4-1A5]
    参阅全部 Annexin V 一抗
  • 描述
    小鼠单克隆抗体[1F4-1A5] to Annexin V
  • 经测试应用适用于: ELISA, WB, IP, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant Human Annexin V protein (NP_001145.1).

  • 阳性对照
    • HeLa lysate and transfected 293T cell line lysates; Human testis tissue; HeLa cells.

性能

应用

Our Abpromise guarantee covers the use of ab117439 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.
WB 1/500 - 1/1000. Predicted molecular weight: 35 kDa.
IP Use at an assay dependent concentration. Suggested: 40 ug of antibody per 100 ul of beads
IHC-P Use a concentration of 5 µg/ml.
ICC/IF Use a concentration of 10 µg/ml.

靶标

  • 功能This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
  • 疾病相关Pregnancy loss, recurrent, 3
  • 序列相似性Belongs to the annexin family.
    Contains 4 annexin repeats.
  • 结构域The [IL]-x-C-x-x-[DE] motif is a proposed target motif for cysteine S-nitrosylation mediated by the iNOS-S100A8/A9 transnitrosylase complex.
    A pair of annexin repeats may form one binding site for calcium and phospholipid.
  • 翻译后修饰S-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Anchorin CII antibody
    • Annexin 5 antibody
    • Annexin A5 antibody
    • Annexin V antibody
    • Annexin-5 antibody
    • ANX A5 antibody
    • ANX5 antibody
    • ANXA5 antibody
    • ANXA5_HUMAN antibody
    • Calphobindin I antibody
    • CBP-I antibody
    • Endonexin II antibody
    • ENX2 antibody
    • Lipocortin V antibody
    • PAP I antibody
    • PAP-I antibody
    • Placental anticoagulant protein 4 antibody
    • Placental anticoagulant protein I antibody
    • PLACENTAL PROTEIN 4 antibody
    • Pp4 antibody
    • Thromboplastin inhibitor antibody
    • VAC-alpha antibody
    • Vascular anticoagulant-alpha antibody
    see all

Anti-Annexin V antibody [1F4-1A5] 图像

  • Anti-Annexin V antibody [1F4-1A5] (ab117439) + HeLa cell lysate

    Predicted band size : 35 kDa
  • All lanes : Anti-Annexin V antibody [1F4-1A5] (ab117439)

    Lane 1 : 293T cell line, transfected with Annexin V
    Lane 2 : 293T cell line, non transfected


    Predicted band size : 35 kDa
  • ab117439, at 5 µg/ml, staining Annexin V in Formalin-fixed, Paraffin-embedded Human Testis tissue by Immunohistochemistry
  • ab117439 at 10µg/ml dilution staining Annexin V in HeLa cells by Immunofluorescence.
  • Western blot of immunoprecipitate of Annexin V transfected lysate using ab117439 and Protein A Magnetic Bead.

Anti-Annexin V antibody [1F4-1A5] (ab117439)参考文献

ab117439 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. I can confirm that the image on our website shows HEK 293T cells transfected either with ANXA5 or empty vector. They were not knockdown cells.
I was unable to find any literature addressing the endogenous levels of Anne...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"