概述

  • 产品名称Anti-Annexin A11抗体
    参阅全部 Annexin A11 一抗
  • 描述
    山羊多克隆抗体to Annexin A11
  • 特异性This antibody is expected to recognise all three human isoforms.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide: YPGYPPPPGGYPP, corresponding to N terminal amino acids 3-15 of Annexin A11 from N Terminus of the protein sequence according to NP_001148; NP_665875; NP_665876

  • 阳性对照
    • HeLa lysate.

性能

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应用

Our Abpromise guarantee covers the use of ab4121 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明Western Blot: approx 55 kDa band seen in HeLa lysate (Predicted MW of approx. 58 kDa according to NP_001148).
    Recommended for use at 0.2-1.0µg/ml.
  • 靶标

    • 功能Binds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation and completion of the terminal phase of cytokinesis.
    • 序列相似性Belongs to the annexin family.
      Contains 4 annexin repeats.
    • 结构域A pair of annexin repeats may form one binding site for calcium and phospholipid.
    • 细胞定位Cytoplasm. Melanosome. Nucleus envelope. Nucleus > nucleoplasm. Cytoplasm > cytoskeleton > spindle. Found throughout the nucleoplasm at interphase and during mitosis concentrates around the mitotic apparatus (By similarity). Elevation of intracellular calcium causes relocalization from the nucleoplasm to the nuclear envelope, with little effect on the cytoplasmic pool. Localization to the nuclear envelope is cell-cycle dependent.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 56 kDa autoantigen antibody
      • Annexin A11 antibody
      • Annexin XI antibody
      • Annexin-11 antibody
      • AnnexinA11 antibody
      • AnnexinXI antibody
      • ANX 11 antibody
      • ANX A11 antibody
      • ANX11 antibody
      • ANX11_HUMAN antibody
      • ANXA 11 antibody
      • ANXA11 antibody
      • Autoantigen 56 kD antibody
      • Calcyclin associated annexin 50 antibody
      • Calcyclin-associated annexin 50 antibody
      • CAP 50 antibody
      • CAP-50 antibody
      • CAP50 antibody
      • OTTHUMP00000059806 antibody
      see all

    Anti-Annexin A11 antibody 图像

    • All lanes : Anti-Annexin A11 antibody (ab4121) at 0.01 µg/ml

      Lane 1 : HeLa lysates (in RIPA buffer)
      Lane 2 : Jurkat lysates (in RIPA buffer)

      Lysates/proteins at 35 µg per lane.


      Observed band size : 54 kDa (why is the actual band size different from the predicted?)

      Primary incubation was 1 hour.

      Detected by chemiluminescence.

    Anti-Annexin A11 antibody (ab4121)参考文献

    ab4121 has not yet been referenced specifically in any publications.

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