概述

  • 产品名称Anti-Annexin A1抗体
    参阅全部 Annexin A1 一抗
  • 描述
    兔多克隆抗体to Annexin A1
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1-198 of Human Annexin A1 (AAH01275).

  • 阳性对照
    • H1299 whole cell lysate, A431, HeLa or MOLT4 lysates Cal27 xenograft (IHC-P) and HeLa cells (IF)

性能

应用

Our Abpromise guarantee covers the use of ab97485 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 39 kDa.
IHC-P 1/100 - 1/500.
ICC/IF 1/100 - 1/200.

靶标

  • 功能Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
  • 序列相似性Belongs to the annexin family.
    Contains 4 annexin repeats.
  • 结构域A pair of annexin repeats may form one binding site for calcium and phospholipid.
  • 翻译后修饰Phosphorylated by protein kinase C, epidermal growth factor receptor/kinase and TRPM7. Phosphorylation results in loss of the inhibitory activity.
  • 细胞定位Nucleus. Cytoplasm. Cell projection > cilium. Basolateral cell membrane. Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Annexin 1 antibody
    • Annexin A1 antibody
    • Annexin I (lipocortin I) antibody
    • Annexin I antibody
    • Annexin-1 antibody
    • AnnexinA1 antibody
    • AnnexinI antibody
    • ANX 1 antibody
    • ANX A1 antibody
    • ANX1 antibody
    • ANXA 1 antibody
    • ANXA1 antibody
    • ANXA1 protein antibody
    • ANXA1_HUMAN antibody
    • Calpactin 2 antibody
    • Calpactin II antibody
    • Calpactin-2 antibody
    • CalpactinII antibody
    • Chromobindin 9 antibody
    • Chromobindin-9 antibody
    • Chromobindin9 antibody
    • HGNC:533 antibody
    • Lipocortin 1 antibody
    • Lipocortin I antibody
    • Lipocortin1 antibody
    • LipocortinI antibody
    • LPC 1 antibody
    • LPC1 antibody
    • p35 antibody
    • Phospholipase A2 inhibitory protein antibody
    see all

Anti-Annexin A1 antibody 图像

  • Anti-Annexin A1 antibody (ab97485) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

    Predicted band size : 39 kDa
  • Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using ab97485 at 1/200 dilution, lower image merged with DNA probe.
  • Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using ab97485 at 1/500 dilution.

Anti-Annexin A1 antibody (ab97485)参考文献

ab97485 has not yet been referenced specifically in any publications.

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