概述

  • 产品名称Anti-Annexin A1抗体
    参阅全部 Annexin A1 一抗
  • 描述
    兔多克隆抗体to Annexin A1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: a wide range of other species
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human Annexin A1.

    (Peptide available as ab47659.)

  • 阳性对照
    • ab46686 gave a positive result in THP1 Whole Cell Lysate.

性能

应用

Our Abpromise guarantee covers the use of ab46686 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/250. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa).

靶标

  • 功能Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
  • 序列相似性Belongs to the annexin family.
    Contains 4 annexin repeats.
  • 结构域A pair of annexin repeats may form one binding site for calcium and phospholipid.
  • 翻译后修饰Phosphorylated by protein kinase C, epidermal growth factor receptor/kinase and TRPM7. Phosphorylation results in loss of the inhibitory activity.
  • 细胞定位Nucleus. Cytoplasm. Cell projection > cilium. Basolateral cell membrane. Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Annexin 1 antibody
    • Annexin A1 antibody
    • Annexin I (lipocortin I) antibody
    • Annexin I antibody
    • Annexin-1 antibody
    • AnnexinA1 antibody
    • AnnexinI antibody
    • ANX 1 antibody
    • ANX A1 antibody
    • ANX1 antibody
    • ANXA 1 antibody
    • ANXA1 antibody
    • ANXA1 protein antibody
    • ANXA1_HUMAN antibody
    • Calpactin 2 antibody
    • Calpactin II antibody
    • Calpactin-2 antibody
    • CalpactinII antibody
    • Chromobindin 9 antibody
    • Chromobindin-9 antibody
    • Chromobindin9 antibody
    • HGNC:533 antibody
    • Lipocortin 1 antibody
    • Lipocortin I antibody
    • Lipocortin1 antibody
    • LipocortinI antibody
    • LPC 1 antibody
    • LPC1 antibody
    • p35 antibody
    • Phospholipase A2 inhibitory protein antibody
    see all

Anti-Annexin A1 antibody 图像

  • Anti-Annexin A1 antibody (ab46686) at 1/250 dilution + THP1 whole cell lysate (ab7913) at 10 µg

    Secondary
    IRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilution

    Performed under reducing conditions.

    Predicted band size : 39 kDa
    Observed band size : 39 kDa
    Additional bands at : 26 kDa,50 kDa. We are unsure as to the identity of these extra bands.

Anti-Annexin A1 antibody (ab46686)参考文献

ab46686 has not yet been referenced specifically in any publications.

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