概述

  • 产品名称Anti-ANKRD17抗体
    参阅全部 ANKRD17 一抗
  • 描述
    兔多克隆抗体to ANKRD17
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Guinea pig, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Bat, Elephant
  • 免疫原

    Synthetic peptide, corresponding to a region between amino acids 1550-1600 of Human ANKRD17 (NP_115593.3, GeneID 26057).

  • 阳性对照
    • Human Controls: Breast Carcinoma, Colon Carcinoma, Ovarian Carcinoma, Prostate Carcinoma, Skin Basal Cell Carcinoma, Testicular Seminoma
  • 常规说明Immunoglobulin concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.

性能

应用

Our Abpromise guarantee covers the use of ab105112 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

靶标

  • 功能Could play pivotal roles in cell cycle and DNA regulation (PubMed:19150984). Involved in innate immune defense against viruse by positively regulating the viral dsRNA receptors DDX58 and IFIH1 signaling pathways (PubMed:22328336). Involves in NOD2- and NOD1-mediated responses to bacteria suggesting a role in innate antibacterial immune pathways too (PubMed:23711367). Target of enterovirus 71 which is the major etiological agent of HFMD (hand, foot and mouth disease) (PubMed:17276651). Could play a central role for the formation and/or maintenance of the blood vessels of the circulation system.
  • 组织特异性Ubiquitously expressed.
  • 序列相似性Contains 25 ANK repeats.
    Contains 1 KH domain.
  • 翻译后修饰Phosphorylated by CDK2.
  • 细胞定位Cytoplasm. Nucleus. Detected around the nucleolus. Localized on chromatin in a cell cycle-dependent manner.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ANKRD 17 antibody
    • ANKRD17 antibody
    • Ankyrin repeat domain protein 17 antibody
    • Ankyrin repeat domain-containing protein 17 antibody
    • ANR17_HUMAN antibody
    • FLJ22206 antibody
    • Gene trap ankyrin repeat antibody
    • Gene trap ankyrin repeat protein antibody
    • GTAR antibody
    • KIAA0697 antibody
    • NY BR 16 antibody
    • NY-BR-16 antibody
    • Serologically defined breast cancer antigen NY-BR-16 antibody
    see all

Anti-ANKRD17 antibody 图像

  • ab105112 at 1/250 dilution staining ANKRD17 in Human breast carcinoma by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining
  • ab105112 at 1/250 dilution staining ANKRD17 in Human prostate carcinoma by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining

Anti-ANKRD17 antibody (ab105112)参考文献

ab105112 has not yet been referenced specifically in any publications.

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