Anti-Angiotensin II Type 1 Receptor抗体(ab97571)


  • 产品名称Anti-Angiotensin II Type 1 Receptor抗体
    参阅全部 Angiotensin II Type 1 Receptor 一抗
  • 描述
    兔多克隆抗体to Angiotensin II Type 1 Receptor
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Sheep, Rabbit, Cow, Dog, Pig, Chimpanzee
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human Angiotensin II Type 1 Receptor.

  • 阳性对照
    • This antibody gave a positive signal in Mouse Liver tissue lysate. This antibody gave a positive result in IHC in the following FFPE tissue: Human normal lung.



Our Abpromise guarantee covers the use of ab97571 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).
IHC-P Use a concentration of 10 µg/ml.


  • 功能Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
  • 组织特异性Liver, lung, adrenal and adrenocortical adenomas.
  • 疾病相关Defects in AGTR1 are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 翻译后修饰C-terminal Ser or Thr residues may be phosphorylated.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AG2S antibody
    • Agtr 1 antibody
    • Agtr1 antibody
    • AGTR1_HUMAN antibody
    • Agtr1a antibody
    • AGTR1B antibody
    • Ang II antibody
    • Angiotensin II receptor type 1 antibody
    • Angiotensin II type-1 receptor antibody
    • Angiotensin receptor 1 antibody
    • Angiotensin receptor 1B antibody
    • AT 1B antibody
    • AT 1r antibody
    • AT1 antibody
    • At1a antibody
    • AT1AR antibody
    • AT1B antibody
    • AT1BR antibody
    • AT1R antibody
    • AT2R1 antibody
    • AT2R1A antibody
    • AT2R1B antibody
    • HAT1R antibody
    • Type 1 angiotensin II receptor antibody
    • Type 1B angiotensin II receptor antibody
    • Type-1 angiotensin II receptor antibody
    see all

Anti-Angiotensin II Type 1 Receptor antibody 图像

  • Anti-Angiotensin II Type 1 Receptor antibody (ab97571) at 1 µg/ml (Milk Blocked 3%) + Liver (Mouse) Tissue Lysate at 20 µg

    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 41 kDa
    Observed band size : 41 kDa
    Additional bands at : 18 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 20 minutes
  • IHC image of Angiotensin II Type 1 Receptor staining in Human normal lung formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab97571, 10µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

    For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Angiotensin II Type 1 Receptor antibody (ab97571)参考文献

ab97571 has not yet been referenced specifically in any publications.

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