Anti-Angiotensin II Type 1 Receptor抗体(ab31667)

概述

• 产品名称
  Anti-Angiotensin II Type 1 Receptor抗体
  参阅全部 Angiotensin II Type 1 Receptor 一抗
• 描述
  羊多克隆抗体to Angiotensin II Type 1 Receptor
• 特异性
  Highly reactive and specific to human Angiotensin Factor-1 receptor.
• 经测试应用
  适用于: ELISA, WBmore details
• 种属反应性
  与反应: Human
  
• 免疫原

  Angiotensin Type I Receptor (Fusion Protein).

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• 存储溶液
  Preservative: None
  Constituents: PBS, pH 7.4.
• Concentration information loading...
• 纯度
  Protein G purified
• 克隆
  多克隆
• 同种型
  IgG
• 研究领域
  • Cardiovascular
  • Blood
  • Other

  • Signal Transduction
  • Signaling Pathway
  • Lipid Signaling
  • PLC

  • Signal Transduction
  • Metabolism
  • Vitamins / Minerals

  • Cancer
  • Invasion/microenvironment
  • Angiogenesis
  • Angiogenic growth factors

  • Cardiovascular
  • Blood
  • Blood Pressure regulation

  • Cardiovascular
  • Vasculature
  • Vasoconstriction
  • Other

  • Cancer
  • Cancer Metabolism
  • Cellular metabolic process

  • Metabolism
  • Types of disease
  • Cancer

应用

靶标

• 功能
  Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
• 组织特异性
  Liver, lung, adrenal and adrenocortical adenomas.
• 疾病相关
  Defects in AGTR1 are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).
• 序列相似性
  Belongs to the G-protein coupled receptor 1 family.
• 翻译后修饰
  C-terminal Ser or Thr residues may be phosphorylated.
• 细胞定位
  Cell membrane.

• Target information above from: UniProt accession P30556 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 185 Human
  • Omim: 106165 Human
  • SwissProt: P30556 Human
  • Unigene: 477887 Human
  • Unigene: 728754 Human
• 别名
  • AG2S antibody
  • Agtr 1 antibody
  • Agtr1 antibody

  • AGTR1_HUMAN antibody
  • Agtr1a antibody
  • AGTR1B antibody
  • Ang II antibody
  • Angiotensin II receptor type 1 antibody
  • Angiotensin II type-1 receptor antibody
  • Angiotensin receptor 1 antibody
  • Angiotensin receptor 1B antibody
  • AT 1B antibody
  • AT 1r antibody
  • AT1 antibody
  • At1a antibody
  • AT1AR antibody
  • AT1B antibody
  • AT1BR antibody
  • AT1R antibody
  • AT2R1 antibody
  • AT2R1A antibody
  • AT2R1B antibody
  • HAT1R antibody
  • Type 1 angiotensin II receptor antibody
  • Type 1B angiotensin II receptor antibody
  • Type-1 angiotensin II receptor antibody

  see all

实验方案

• Western blot protocols