概述
- 产品名称Anti-Angiotensin II Type 1 Receptor抗体
参阅全部 Angiotensin II Type 1 Receptor 一抗 - 描述羊多克隆抗体to Angiotensin II Type 1 Receptor
- 特异性Highly reactive and specific to human Angiotensin Factor-1 receptor.
- 经测试应用适用于: ELISA, WBmore details
- 种属反应性与反应: Human
- 免疫原
Angiotensin Type I Receptor (Fusion Protein).
性能
- 形式Liquid
- 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
- 存储溶液Preservative: None
Constituents: PBS, pH 7.4. -
Concentration information loading... - 纯度Protein G purified
- 克隆多克隆
- 同种型IgG
- 研究领域
应用
Our Abpromise guarantee covers the use of ab31667 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ELISA | 1/500 - 1/2000. | |
| WB | 1/50 - 1/1000. Predicted molecular weight: 40 kDa. |
靶标
- 功能Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
- 组织特异性Liver, lung, adrenal and adrenocortical adenomas.
- 疾病相关Defects in AGTR1 are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).
- 序列相似性Belongs to the G-protein coupled receptor 1 family.
- 翻译后修饰C-terminal Ser or Thr residues may be phosphorylated.
- 细胞定位Cell membrane.
- Information by UniProt
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数据库链接
- Entrez Gene: 185 Human
- Omim: 106165 Human
- SwissProt: P30556 Human
- Unigene: 477887 Human
- Unigene: 728754 Human
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别名
- AG2S antibody
- Agtr 1 antibody
- Agtr1 antibody
see all
Anti-Angiotensin II Type 1 Receptor antibody (ab31667)参考文献
ab31667 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"