存放说明 Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
存储溶液 Preservative: 0.02% Sodium azide Constituent: 99% PBS
Concentration information loading...
纯度 Immunogen affinity purified
Immunizing Peptide (Blocking)
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
功能 Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
组织特异性 Liver, lung, adrenal and adrenocortical adenomas.
疾病相关 Defects in AGTR1 are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).
序列相似性 Belongs to the G-protein coupled receptor 1 family.
翻译后修饰 C-terminal Ser or Thr residues may be phosphorylated.
细胞定位 Cell membrane.
Information by UniProt
Agtr 1 antibody
Anti-Angiotensin II Type 1 Receptor antibody 图像
Western blot - Anti-Angiotensin II Type 1 Receptor antibody (ab124505)
Lane 1 : Anti-Angiotensin II Type 1 Receptor antibody (ab124505) at 1 µg/ml Lane 2 : Anti-Angiotensin II Type 1 Receptor antibody (ab124505) at 2 µg/ml Lane 1 : Mouse kidney tissue lysate Lane 2 : Mouse kidney tissue lysate Lysates/proteins at 15 µg per lane. Predicted band size : 41 kDa
Immunocytochemistry/ Immunofluorescence-Anti-Angiotensin II Type 1 Receptor antibody(ab124505)
Immunofluorescence of AGTR1 in mouse kidney cells using ab124505 at 20 ug/ml.
Immunohistochemistry - Anti-Angiotensin II Type 1 Receptor antibody (ab124505)
Immunohistochemical analysis of mouse kidney tissue section labelling Angiotensin II Type 1 Receptor with ab124505, at 2.5 µg/ml.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Angiotensin II Type 1 Receptor antibody (ab124505)
ab124505, at 2.5 µg/ml, staining Angiotensin II Type 1 Receptor in paraffin-embedded Mouse kidney tissue by Immunohistochemistry.
Anti-Angiotensin II Type 1 Receptor antibody (ab124505)参考文献
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