Anti-Angiotensin Converting Enzyme 2抗体- N-terminal (ab76526)


  • 产品名称Anti-Angiotensin Converting Enzyme 2抗体- N-terminal
    参阅全部 Angiotensin Converting Enzyme 2 一抗
  • 描述
    兔多克隆抗体to Angiotensin Converting Enzyme 2 - N-terminal
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide selected from the N-terminal region of human ACE2 conjugated to KLH

  • 阳性对照
    • WB: K562 cell line lysate IHC: Human cancer tissue (hepatocarcinoma) and human testis tissue



Our Abpromise guarantee covers the use of ab76526 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/250. Predicted molecular weight: 92 kDa.
ELISA 1/1000.
IHC-P 1/50 - 1/100.


  • 功能Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
  • 组织特异性Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level). Expressed in heart, kidney, testis, and gastrointestinal system.
  • 序列相似性Belongs to the peptidase M2 family.
  • 翻译后修饰N-glycosylation on Asn-90 may limit SARS infectivity.
  • 细胞定位Secreted and Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ACE 2 antibody
    • ACE related carboxypeptidase antibody
    • ACE-related carboxypeptidase antibody
    • ACE2 antibody
    • ACE2_HUMAN antibody
    • ACEH antibody
    • Angiotensin converting enzyme 2 antibody
    • Angiotensin converting enzyme homolog antibody
    • Angiotensin converting enzyme like protein antibody
    • Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2 antibody
    • Angiotensin I converting enzyme 2 antibody
    • Angiotensin-converting enzyme homolog antibody
    • DKFZP434A014 antibody
    • EC 3.4.17 antibody
    • metalloprotease MPROT 15 antibody
    • Metalloprotease MPROT15 antibody
    • OTTHUMP00000022963 antibody
    • Processed angiotensin-converting enzyme 2 antibody
    see all

Anti-Angiotensin Converting Enzyme 2 antibody - N-terminal 图像

  • Anti-Angiotensin Converting Enzyme 2 antibody - N-terminal (ab76526) at 1/60 dilution + K562 cell line lysate at 35 µg

    Predicted band size : 92 kDa
    Observed band size : 95 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 55 kDa. We are unsure as to the identity of these extra bands.
  • Formalin-fixed and paraffin-embedded human cancer tissue (hepatocarcinoma), stained with ab76526, at 1/50 dilution, using a peroxidase-conjugated secondary antibody and AEC staining.
  • Formalin-fixed and paraffin-embedded human testis tissue, stained with ab76526, at 1/50 dilution, using a peroxidase-conjugated secondary antibody and DAB staining.

Anti-Angiotensin Converting Enzyme 2 antibody - N-terminal (ab76526)参考文献

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