Anti-Angiotensin Converting Enzyme 2抗体[EPR4436] (ab108209)


  • 产品名称Anti-Angiotensin Converting Enzyme 2抗体[EPR4436]
    参阅全部 Angiotensin Converting Enzyme 2 一抗
  • 描述
    兔单克隆抗体[EPR4436] to Angiotensin Converting Enzyme 2
  • 经测试应用适用于: WB, IP, IHC-Pmore details
    不适用于: Flow Cyt or ICC
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human Angiotensin Converting Enzyme 2.

  • 阳性对照
    • Fetal kidney and Human testis lysates; Human kidney tissue and Human testis tissue
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.



Our Abpromise guarantee covers the use of ab108209 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 92 kDa.
IP 1/10 - 1/100.
IHC-P 1/100 - 1/250. Antigen retrieval is recommended; heat up to 98 °C, below boiling, and then let cool for 10-20 minutes. The use of an HRP/AP polymerized secondary antibody is recommended.
  • 应用说明Is unsuitable for Flow Cyt or ICC.
  • 靶标

    • 功能Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
    • 组织特异性Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level). Expressed in heart, kidney, testis, and gastrointestinal system.
    • 序列相似性Belongs to the peptidase M2 family.
    • 翻译后修饰N-glycosylation on Asn-90 may limit SARS infectivity.
    • 细胞定位Secreted and Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ACE 2 antibody
      • ACE related carboxypeptidase antibody
      • ACE-related carboxypeptidase antibody
      • ACE2 antibody
      • ACE2_HUMAN antibody
      • ACEH antibody
      • Angiotensin converting enzyme 2 antibody
      • Angiotensin converting enzyme homolog antibody
      • Angiotensin converting enzyme like protein antibody
      • Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2 antibody
      • Angiotensin I converting enzyme 2 antibody
      • Angiotensin-converting enzyme homolog antibody
      • DKFZP434A014 antibody
      • EC 3.4.17 antibody
      • metalloprotease MPROT 15 antibody
      • Metalloprotease MPROT15 antibody
      • OTTHUMP00000022963 antibody
      • Processed angiotensin-converting enzyme 2 antibody
      see all

    Anti-Angiotensin Converting Enzyme 2 antibody [EPR4436] 图像

    • All lanes : Anti-Angiotensin Converting Enzyme 2 antibody [EPR4436] (ab108209)

      Lane 1 : Human fetal kidney lysate
      Lane 2 : Human testis lysates

      Lysates/proteins at 10 µg per lane.

      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 92 kDa
    • ab108209, at a 1/100 dilution, staining Angiotensin Converting Enzyme 2 in paraffin embedded Human kidney tissue by Immunohistochemistry.
    • ab108209, at a 1/100 dilution, staining Angiotensin Converting Enzyme 2 in paraffin embedded Human testis tissue by immunohistochemistry.

    Anti-Angiotensin Converting Enzyme 2 antibody [EPR4436] (ab108209)参考文献

    ab108209 has not yet been referenced specifically in any publications.

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