Anti-Angiopoietin 2抗体(ab125692)

概述

  • 产品名称Anti-Angiopoietin 2抗体
    参阅全部 Angiopoietin 2 一抗
  • 描述
    兔多克隆抗体to Angiopoietin 2
  • 特异性At least three isoforms of ANGPT2 are known to exist; this antibody will detect all three isoforms.
  • 经测试应用适用于: ICC, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to 18 amino acids near the carboxy terminus of Human Angiopoietin 2 protein (O15123).

  • 阳性对照
    • Human Liver Tissue Lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab125692 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC Use a concentration of 2.5 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 56 kDa.Can be blocked with Human Angiopoietin 2 peptide (ab172727).

靶标

  • 功能Can induce tyrosine phosphorylation of TIE2. Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
  • 序列相似性Contains 1 fibrinogen C-terminal domain.
  • 结构域The Fibrinogen C-terminal domain mediates interaction with the TEK/TIE2 receptor.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AGPT 2 antibody
    • Agpt2 antibody
    • ANG 2 antibody
    • ANG-2 antibody
    • ANG2 antibody
    • Angiopoietin 2a antibody
    • Angiopoietin 2B antibody
    • Angiopoietin-2 antibody
    • Angiopoietin2 antibody
    • ANGP2_HUMAN antibody
    • ANGPT 2 antibody
    • Angpt2 antibody
    • Tie2 ligand antibody
    see all

Anti-Angiopoietin 2 antibody 图像

  • Lane 1 : Anti-Angiopoietin 2 antibody (ab125692) at 1 µg/ml
    Lane 2 : Anti-Angiopoietin 2 antibody (ab125692) at 2 µg/ml

    Lane 1 : Human liver tissue lysate
    Lane 2 : Human liver tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 56 kDa
  • Immunohistochemistry of Angiopoietin 2 in mouse liver tissue with ab125692 antibody at 2.5 ug/mL.

Anti-Angiopoietin 2 antibody (ab125692)参考文献

ab125692 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab125692.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"