Anti-Angiopoietin 1抗体(ab94684)
Key features and details
- Rabbit polyclonal to Angiopoietin 1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Angiopoietin 1抗体
参阅全部 Angiopoietin 1 一抗 -
描述
兔多克隆抗体to Angiopoietin 1 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
A 15 amino acid synthetic peptide from near the N terminal residues of Human Angiopoietin 1 (NM_001146.3).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Reconstitute with 200ul distilled sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary. -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 2% BSA, PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab94684于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (1) |
1/200 - 1/500. Predicted molecular weight: 58 kDa.
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IHC-P |
1/50 - 1/20.
|
说明 |
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WB
1/200 - 1/500. Predicted molecular weight: 58 kDa. |
IHC-P
1/50 - 1/20. |
靶标
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功能
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development. -
序列相似性
Contains 1 fibrinogen C-terminal domain. -
翻译后修饰
Glycosylated. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 284 Human
- Omim: 601667 Human
- SwissProt: Q15389 Human
- Unigene: 369675 Human
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别名
- AGP 1 antibody
- AGP1 antibody
- AGPT antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab94684 被引用在 4 文献中.
- Harbuzariu A et al. Neuregulin-1/ErbB4 signaling modulates Plasmodium falciparum HRP2-induced damage to brain cortical organoids. iScience 25:104407 (2022). PubMed: 35663028
- Gimble JM et al. A Novel, Sterilized Microvascular Tissue Product Improves Healing in a Murine Pressure Ulcer Model. Plast Reconstr Surg Glob Open 6:e2010 (2018). PubMed: 30881803
- Sun L et al. Angiopoietin-1 facilitates recovery of hematopoiesis in radiated mice. Am J Transl Res 8:2011-21 (2016). PubMed: 27347310
- Fang JH et al. A novel vascular pattern promotes metastasis of hepatocellular carcinoma in an epithelial-mesenchymal transition-independent manner. Hepatology 62:452-65 (2015). PubMed: 25711742